Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 1/20 | 0.46 |
| ▸ | ATP4B | P51164 | 1/20 | 0.46 |
| ▸ | GUCY1B2 | O75343 | 16/20 | 0.45 |
| ▸ | GUCY1A2 | P33402 | 16/20 | 0.45 |
| ▸ | GUCY1A1 | Q02108 | 16/20 | 0.45 |
| ▸ | GUCY1B1 | Q02153 | 16/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18570328 | 0.88 | CYP3A4 (0.52) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1CYP1A2 | |
| SCHEMBL19492087 | 0.86 | GUCY1B2 (0.43) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1CYP1A2 | |
| SCHEMBL16403535 | 0.86 | GUCY1B2 (0.45) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1CYP1A2 | |
| SCHEMBL17803134 | 0.85 | GUCY1B2 (0.42) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1CYP1A2 | |
| SCHEMBL16403049 | 0.84 | GUCY1B2 (0.47) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL16402801 | 0.84 | GUCY1B2 (0.53) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL16402956 | 0.84 | GUCY1B2 (0.46) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1CYP1A2 | |
| SCHEMBL19012013 | 0.84 | ATP4A (0.48) | ATP4AATP4BGUCY1B2GUCY1A2GUCY1A1 | |
| SCHEMBL20528798 | 0.83 | ATP4A (0.67) | ATP4AATP4BGUCY1B2GUCY1A2GUCY1A1 | |
| SCHEMBL16403544 | 0.83 | GUCY1B2 (0.45) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3227287-B1 | HETEROARYL-SUBSTITUTED IMIDAZO[1,2-A]PYRIDINES AND THEIR USE | Bayer Pharma AG (DE) | 2019-08-07 | — | — | EP | disclosed |
| WO-2018184976-A1 | SUBSTITUTED IMIDAZO[1,2-A]PYRIDINECARBOXAMIDES AND USE OF SAME | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-10-11 | — | — | WO | disclosed |