SCHEMBL190146

SCHEMBL190146

CC(C)c1ccc(CBr)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.52
RAB9A P51151 4/20 0.44
NPC1 O15118 3/20 0.44
TRPA1 O75762 1/20 0.43
ALDH1A1 P00352 1/20 0.43
TSHR P16473 1/20 0.43
PYCR1 P32322 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
TYR P14679 2/20 0.41
HTR1D P28221 1/20 0.40
HTR1B P28222 1/20 0.40
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
RXRA P19793 1/20 0.38
RXRB P28702 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
BCHE P06276 1/20 0.38
ACHE P22303 1/20 0.38
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7550160 0.84 ESR1 (0.46) IDO1RAB9ANPC1TRPA1ALDH1A1
Propionic Acid SCHEMBL29125221 0.84 USP5 (0.47) RAB9ANPC1ALDH1A1TSHRL3MBTL1
SCHEMBL7461724 0.80 IDO1 (0.48) IDO1RAB9ANPC1ALDH1A1PYCR1
SCHEMBL17816125 0.80 TSHR (0.40) IDO1RAB9ANPC1TRPA1ALDH1A1
SCHEMBL13690219 0.78 LMNA (0.41) TRPA1ALDH1A1TSHRHTTKMT2A
SCHEMBL2272987 0.78 TSHR (0.48) IDO1TRPA1ALDH1A1TSHRL3MBTL1
SCHEMBL3956146 0.78 IDO1 (0.56) IDO1RAB9ANPC1ALDH1A1TSHR
SCHEMBL10729588 0.78 IDO1 (0.56) IDO1RAB9ANPC1ALDH1A1PYCR1
SCHEMBL24074493 0.77 IDO1 (0.45) IDO1RAB9ANPC1ALDH1A1PYCR1
SCHEMBL13742741 0.77 ESR1 (0.41) IDO1TRPA1ALDH1A1TSHRACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 364 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119101052-A Matrine-triazole derivative and synthesis method thereof 吉林医药学院 2024-12-10 CN claimed
CN-115805101-B Catalyst for preparing hydroxy aryl ketone and preparation method and application thereof 中国石油化工股份有限公司 2024-11-29 CN claimed
CN-117779469-A Construction method of host and guest of photodynamic/quaternary ammonium salt/boric acid antibacterial composite PET fiber coating 浙江豪欣纺织有限公司 2024-03-29 CN claimed
CN-117776923-A Crocetin diester compound and application thereof in liver cancer cell resistance 常州大学 2024-03-29 CN claimed
CN-116640106-B Phenylpiperazine compound and preparation method and application thereof 郑州大学 2024-03-08 CN claimed
CN-116640106-A Phenylpiperazine compound and preparation method and application thereof 郑州大学 2023-08-25 CN claimed
CN-115872939-A 2,3-dihydroquinazoline-4 (1H) -ketone derivative and preparation and application thereof 武汉科技大学 2023-03-31 CN claimed
CN-115805101-A Catalyst for preparing hydroxy arone and preparation method and application thereof 中国石油化工股份有限公司 2023-03-17 CN claimed
US-4248779-A REACTING CARBONYL SULFIDE WITH A SECONDARY AMINE AND REACTING THE AMINE SALT WITH A HALOHYDROCARBON IHARA CHEMICAL INDUSTRY COMPANY, LIMITED (JP) 1981-02-03 US claimed
CN-122010944-A TBC1D 2-targeted aromatic methyl alkenyl matrine derivative and preparation method and application thereof 广西大学 2026-05-12 CN disclosed
EP-4085930-B1 HYDROXYLATED POLYAMINE DERIVATIVES AS TRANSFECTION REAGENTS FOR RNA BIONTECH DELIVERY TECH GMBH (DE) 2026-04-22 EP disclosed
WO-2025129168-A1 TRIAZOLONE INHIBITORS OF NICOTINAMIDE N-METHYLTRANSFERASE AND THEIR THERAPEUTIC USES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2025-06-19 WO disclosed
CN-119968368-A Amide compound, preparation method, pharmaceutical composition and application thereof 中国科学院上海药物研究所 2025-05-09 CN disclosed
CN-119330871-A Synthesis and application of cycloheptanone compound 江苏中旗科技股份有限公司 2025-01-21 CN disclosed
US-4971979-A Antiinflammatory agents RHONE-POULENC SANTE (FR) 1990-11-20 US disclosed
US-4886835-A ANTIINFLAMMATORY AGENTS RHONE-POULENC SANTE (FR) 1989-12-12 US disclosed
EP-0075896-B1 PHARMACEUTICAL AMIDES, AND PREPARATION, FORMULATIONS AND USE THEREOF THE WELLCOME FOUNDATION LIMITED (GB) 1986-02-26 EP disclosed
US-4504492-A ENKEPHALINASE INHIBITOR BURROUGHS WELLCOME CO. (US) 1985-03-12 US disclosed
EP-0075896-A2 Pharmaceutical amides, and preparation, formulations and use thereof THE WELLCOME FOUNDATION LIMITED (GB) 1983-04-06 EP disclosed
US-4181733-A ANTIBIOTICS MERCK & CO., INC. (US) 1980-01-01 US disclosed