Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL131361 | 0.80 | ALDH1A1 (0.67) | TSHRTRPA1ALDH1A1TDP1CES2 | |
| SCHEMBL8954829 | 0.80 | TSHR (0.46) | TSHRTRPA1ALDH1A1MAPK1TDP1 | |
| SCHEMBL6398066 | 0.78 | TSHR (0.43) | TSHRTRPA1ALDH1A1CES2CES1 | |
| SCHEMBL3388795 | 0.78 | TRPA1 (0.43) | TSHRTRPA1ALDH1A1CES2CES1 | |
| SCHEMBL19616281 | 0.78 | TSHR (0.43) | TSHRTRPA1ALDH1A1CES2CES1 | |
| SCHEMBL7550160 | 0.78 | ESR1 (0.46) | TSHRTRPA1ALDH1A1MAPK1TDP1 | |
| SCHEMBL9397388 | 0.78 | TSHR (0.43) | TSHRTRPA1ALDH1A1MAPK1TDP1 | |
| SCHEMBL190146 | 0.78 | IDO1 (0.52) | TSHRTRPA1ALDH1A1L3MBTL1IDO1 | |
| SCHEMBL17816125 | 0.74 | TSHR (0.40) | TSHRTRPA1ALDH1A1MAPK1TDP1 | |
| SCHEMBL3098973 | 0.74 | ALDH1A1 (0.40) | TSHRTRPA1ALDH1A1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8710151-B2 | Onium salt-containing polymer | NIPPON SODA CO., LTD. (JP) | 2014-04-29 | — | — | US | disclosed |
| US-20110201759-A1 | ONIUM SALT-CONTAINING POLYMER | NIPPON SODA CO., LTD. (JP) | 2011-08-18 | — | — | US | disclosed |
| EP-2226343-A1 | ONIUM SALT-CONTAINING POLYMER | Nippon Soda Co., Ltd. (JP) | 2010-09-08 | — | — | EP | disclosed |