SCHEMBL19014637

CC[C@@H](CCN(C)CCP(=O)(O)O)Nc1ccc(S(=O)(=O)NC(=O)c2ccc(N3CCN(CC4=C(c5ccc(Cl)cc5)CCC(C)(C)C4)CC3)cc2)cc1S(=O)(=O)C(F)(F)F

nearest known ligand 0.76

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	BCL2L1	Q07817	15/20	0.76

▸	BCL2	P10415	18/20	0.71

▸	BCL2L2	Q92843	3/20	0.68

▸	BAD	Q92934	2/20	0.68

▸	BCL2L11	O43521	1/20	0.68

▸	CYP2C9	P11712	1/20	0.68

▸	MCL1	Q07820	1/20	0.68

▸	ASPH	Q12797	1/20	0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL19014619	0.93	BCL2L1 (0.80)	BCL2L1BCL2BCL2L2BADBCL2L11
SCHEMBL19014936	0.88	BCL2L1 (0.76)	BCL2L1BCL2BCL2L2BADBCL2L11
SCHEMBL19014626	0.88	BCL2L1 (0.82)	BCL2L1BCL2BCL2L2BADBCL2L11
SCHEMBL19503615	0.87	BCL2L1 (0.69)	BCL2L1BCL2BCL2L2BADBCL2L11
SCHEMBL19014616	0.87	BCL2L1 (0.77)	BCL2L1BCL2BCL2L2BADBCL2L11
SCHEMBL20992957	0.87	BCL2L1 (0.83)	BCL2L1BCL2BCL2L2BADBCL2L11
SCHEMBL19503617	0.87	BCL2L1 (0.70)	BCL2L1BCL2BCL2L2BADBCL2L11
SCHEMBL29092638	0.85	BCL2L1 (0.80)	BCL2L1BCL2BCL2L2BADBCL2L11
SCHEMBL24985389	0.85	BCL2 (0.86)	BCL2L1BCL2BCL2L2BADBCL2L11
SCHEMBL1567618	0.85	BCL2L1 (0.86)	BCL2L1BCL2BCL2L2BADBCL2L11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2017101851-A1	ACYLSULFONAMIDE DERIVATIVES FOR TREATING SENESCENCE-ASSOCIATED DISEASES AND DISORDERS	UNITY BIOTECHNOLOGY, INC. (US)	2017-06-22	—	—	WO	disclosed