Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 19/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1901472 | 1.00 | PTGDR2 (0.42) | PTGDR2CYP2C9HTR6PTGER2 | |
| SCHEMBL1899630 | 0.91 | PTGDR2 (0.44) | PTGDR2CYP2C9HTR6 | |
| SCHEMBL1899628 | 0.91 | PTGDR2 (0.44) | PTGDR2CYP2C9HTR6 | |
| SCHEMBL2487581 | 0.90 | PTGDR2 (0.42) | PTGDR2CYP2C9HTR6 | |
| SCHEMBL2492264 | 0.89 | OPRM1 (0.43) | PTGDR2HTR6PTGER2 | |
| SCHEMBL1905222 | 0.89 | OPRM1 (0.43) | PTGDR2HTR6PTGER2 | |
| SCHEMBL1902864 | 0.88 | PTGDR2 (0.46) | PTGDR2HTR6 | |
| SCHEMBL1902865 | 0.88 | PTGDR2 (0.46) | PTGDR2HTR6 | |
| SCHEMBL1899238 | 0.86 | PTGDR2 (0.47) | PTGDR2HTR6 | |
| SCHEMBL1899234 | 0.86 | PTGDR2 (0.47) | PTGDR2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2051962-B1 | (3-AMINO-1,2,3,4-TETRAHYDRO-9H-CARBAZOL-9-YL)-ACETIC ACID DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2011-10-26 | — | — | EP | disclosed |
| EP-2316824-A1 | (3-Amino-1,2,3,4-tetrahydro-9H-carbazoI-9-yl)-acetic acid derivates | Actelion Pharmaceuticals Ltd. (CH) | 2011-05-04 | — | — | EP | disclosed |