Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19014868 | 1.00 | MAOA (0.41) | MAOAMAOBMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL19014775 | 0.90 | MAOA (0.40) | MAOAMAOBMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL19014863 | 0.90 | MAOA (0.40) | MAOAMAOBMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL22428825 | 0.88 | MAOA (0.45) | MAOAMAOBMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL19014774 | 0.85 | MAOA (0.47) | MAOAMAOBMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL19014864 | 0.85 | MAOA (0.47) | MAOAMAOBMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL19014870 | 0.84 | MAOA (0.36) | MAOAMAOBMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL19014904 | 0.78 | SIGMAR1 (0.40) | MAOAMAOBALDH1A1MAPK1DRD2 | |
| SCHEMBL19014901 | 0.78 | SIGMAR1 (0.40) | MAOAMAOBALDH1A1MAPK1DRD2 | |
| SCHEMBL26648824 | 0.78 | MAOA (0.50) | MAOAMAOBMTNR1AMTNR1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017101851-A1 | ACYLSULFONAMIDE DERIVATIVES FOR TREATING SENESCENCE-ASSOCIATED DISEASES AND DISORDERS | UNITY BIOTECHNOLOGY, INC. (US) | 2017-06-22 | — | — | WO | disclosed |