SCHEMBL18069214

SCHEMBL18069214

CCCCCCSC(=O)C#Cc1ccc2c3c(cccc13)C(=O)N(OS(C)(=O)=O)C2=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.40
▸ KMT2A Q03164 5/20 0.40
▸ MEN1 O00255 4/20 0.40
▸ POLB P06746 2/20 0.40
▸ L3MBTL1 Q9Y468 2/20 0.40
▸ TDP1 Q9NUW8 2/20 0.34
▸ HDAC1 Q13547 2/20 0.33
▸ HDAC6 Q9UBN7 2/20 0.33
▸ HDAC3 O15379 1/20 0.33
▸ HDAC7 Q8WUI4 1/20 0.33
▸ HDAC2 Q92769 1/20 0.33
▸ HDAC10 Q969S8 1/20 0.33
▸ HDAC11 Q96DB2 1/20 0.33
▸ HDAC8 Q9BY41 1/20 0.33
▸ HDAC5 Q9UQL6 1/20 0.33
▸ NCOR2 Q9Y618 1/20 0.33
▸ ALDH1A1 P00352 5/20 0.32
▸ HTT P42858 3/20 0.32
▸ KDM4E B2RXH2 3/20 0.32
▸ HPGD P15428 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18069173 0.90 MAPT (0.39) MAPTKMT2AMEN1POLBL3MBTL1
SCHEMBL18069204 0.85 KMT2A (0.40) MAPTKMT2AMEN1POLBL3MBTL1
SCHEMBL19014823 0.84 TDP1 (0.33) MAPTKMT2AMEN1POLBL3MBTL1
SCHEMBL18069227 0.83 MAPT (0.37) MAPTKMT2AMEN1POLBL3MBTL1
SCHEMBL18069209 0.82 TDP1 (0.41) MAPTKMT2AMEN1POLBL3MBTL1
SCHEMBL18069183 0.82 TDP1 (0.39) MAPTKMT2AMEN1POLBL3MBTL1
SCHEMBL18069212 0.80 HDAC1 (0.39) MAPTKMT2AMEN1POLBL3MBTL1
SCHEMBL18069175 0.80 TDP1 (0.40) MAPTKMT2AMEN1POLBL3MBTL1
SCHEMBL18069211 0.78 KMT2A (0.38) MAPTKMT2AMEN1POLBL3MBTL1
SCHEMBL18069199 0.78 KMT2A (0.38) MAPTKMT2AMEN1POLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9477150-B2 Sulfonic acid derivative compounds as photoacid generators in resist applications Heraeus Precious Metals North America Daychem LLC (US) 2016-10-25 — — US disclosed
US-20160266487-A1 SULFONIC ACID DERIVATIVE COMPOUNDS AS PHOTOACID GENERATORS IN RESIST APPLICATIONS HERAEUS EPURIO LLC 2016-09-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160266487-A1 SULFONIC ACID DERIVATIVE COMPOUNDS AS PHOTOACID GENERATORS IN RESIST APPLICATIONS ALAD, MPST, ASIC1 MAPT 3437/4885KMT2A 1020/4885MEN1 1317/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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