SCHEMBL1901502

SCHEMBL1901502

Nc1ccc(C(=O)Oc2ccccc2)cc1N

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 7/20 0.55
▸ ALDH1A1 P00352 2/20 0.55
▸ PARP10 Q53GL7 1/20 0.54
▸ NSD2 O96028 1/20 0.54
▸ KMT2A Q03164 4/20 0.54
▸ MEN1 O00255 3/20 0.54
▸ TMPRSS15 P98073 2/20 0.53
▸ ALOX5 P09917 1/20 0.53
▸ PRSS1 P07477 1/20 0.53
▸ ACR P10323 1/20 0.53
▸ SMN1; SMN2 Q16637 2/20 0.49
▸ LMNA P02545 1/20 0.49
▸ TP53 P04637 1/20 0.49
▸ CYP3A4 P08684 1/20 0.49
▸ ADORA3 P0DMS8 1/20 0.49
▸ CHRM1 P11229 1/20 0.49
▸ TBXA2R P21731 1/20 0.49
▸ SLC6A2 P23975 1/20 0.49
▸ PDE4A P27815 1/20 0.49
▸ ADRA1A P35348 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11132960 0.87 MAPT (0.54) MAPTALDH1A1PARP10NSD2KMT2A
SCHEMBL28737846 0.86 NSD2 (0.65) MAPTALDH1A1PARP10NSD2KMT2A
SCHEMBL10599266 0.86 MAPT (0.58) MAPTALDH1A1PARP10NSD2KMT2A
SCHEMBL812882 0.85 PARP10 (0.55) MAPTALDH1A1PARP10NSD2KMT2A
SCHEMBL27205424 0.85 MAPT (0.59) MAPTALDH1A1PARP10NSD2KMT2A
Water SCHEMBL27930155 0.85 MAPT (0.52) MAPTALDH1A1PARP10NSD2KMT2A
SCHEMBL29964074 0.85 MAPT (0.51) MAPTALDH1A1PARP10NSD2KMT2A
SCHEMBL11140597 0.85 MAPT (0.56) MAPTALDH1A1PARP10NSD2KMT2A
SCHEMBL11165263 0.82 ALDH1A1 (0.61) MAPTALDH1A1PARP10NSD2KMT2A
SCHEMBL1901504 0.82 KMT2A (0.64) MAPTALDH1A1PARP10KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9382496-B1 Lubricants with high thermal stability for heat-assisted magnetic recording WESTERN DIGITAL TECHNOLOGIES, INC. (US) 2016-07-05 — — US disclosed
US-9272388-B2 Polishing systems NEXPLANAR CORPORATION (US) 2016-03-01 — — US disclosed
US-20130149945-A1 POLISHING SYSTEMS CMC MATERIALS LLC 2013-06-13 — — US disclosed
US-8383003-B2 Polishing systems NEXPLANAR CORPORATION (US) 2013-02-26 — — US disclosed
US-7950529-B2 Separation membrane made from blends of polyimides with polyimidazoles L'AIR LIQUIDE SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 2011-05-31 — — US disclosed
US-20100078386-A1 Separation Membrane made from Blends of Polyimides with Polyimidazoles L'AIR LIQUIDE SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 2010-04-01 — — US disclosed
US-20090318063-A1 Polishing systems NEXPLANAR CORPORATION (US) 2009-12-24 — — US disclosed
US-5362809-A With liquid crystal copolyesters; melt processable; molded articles, automobile parts, housings, bottles ROHM AND HAAS COMPANY 1994-11-08 — — US disclosed
EP-0594433-A1 Polymer blends containing polyglutarimides ROHM AND HAAS COMPANY (US) 1994-04-27 — — EP disclosed
US-5114579-A Microporous polybenzimidazole membranes between compartments THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1992-05-19 — — US disclosed
US-4460763-A Preparation of small particle polybenzimidazole E. I. DUPONT DE NEMOURS AND COMPANY (US) 1984-07-17 — — US disclosed
US-4448687-A Process for the production of semipermeable polybenzimidazole membranes with low temperature annealing CELANESE CORPORATION (US) 1984-05-15 — — US disclosed
US-4394500-A Bead polymerization process for preparing polybenzimidazole E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-07-19 — — US disclosed
US-4321182-A Stable non-corrosive solution of polybenzimidazole suitable for use in the formation of shaped articles CELANESE CORPORATION (US) 1982-03-23 — — US disclosed
US-4263245-A COMPRISING WET SPINNING, VERTICAL EXTRUSION, BATH FOR COAGULATION AND DRAWING, WASHING, DRYING, AND HEATING; STABILIZATION CELANESE CORPORATION (US) 1981-04-21 — — US disclosed
US-4077906-A Polybenzimidazole fiber supported catalyst CELANESE CORPORATION (US) 1978-03-07 — — US disclosed
US-4066705-A POLYBENZIMIDAZOLE FIBER SUPPORTED CATALYST CELANESE CORPORATION (US) 1978-01-03 — — US disclosed
US-4048139-A ARSENIC THIOARSENATE, COPPER PHTHALOCYANINE, ANATASE TITANIUM DIOXIDE, PIGMENTS CELANESE CORPORATION (US) 1977-09-13 — — US disclosed
US-4020142-A Chemical modification of polybenzimidazole semipermeable CELANESE CORPORATION (US) 1977-04-26 — — US disclosed
US-3942950-A Process for the dyeing of polybenzimidazole fibers with anionic dyestuffs CELANESE CORPORATION (US) 1976-03-09 — — US disclosed
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