SCHEMBL812882

SCHEMBL812882

Nc1ccc(Oc2ccc(C(=O)Oc3ccccc3)cc2)cc1N

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PARP10 Q53GL7 3/20 0.55
▸ NR4A1 P22736 1/20 0.52
▸ SMN1; SMN2 Q16637 2/20 0.50
▸ PRSS1 P07477 1/20 0.50
▸ ACR P10323 1/20 0.50
▸ TMPRSS15 P98073 1/20 0.50
▸ KMT2A Q03164 5/20 0.47
▸ MAPT P10636 5/20 0.47
▸ MEN1 O00255 3/20 0.47
▸ TDP1 Q9NUW8 2/20 0.47
▸ NSD2 O96028 1/20 0.47
▸ ALOX5 P09917 1/20 0.47
▸ TNKS O95271 1/20 0.46
▸ PARP15 Q460N3 1/20 0.46
▸ PARP14 Q460N5 1/20 0.46
▸ TNKS2 Q9H2K2 1/20 0.46
▸ PARP2 Q9UGN5 1/20 0.46
▸ SRD5A2 P31213 1/20 0.46
▸ AKR1C3 P42330 1/20 0.46
▸ ALDH1A1 P00352 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1901504 0.85 KMT2A (0.64) PARP10KMT2AMAPTMEN1TDP1
SCHEMBL1901502 0.85 MAPT (0.55) PARP10SMN1; SMN2PRSS1ACRTMPRSS15
SCHEMBL9240757 0.85 PARP10 (0.67) PARP10SMN1; SMN2PRSS1ACRTMPRSS15
SCHEMBL8209000 0.85 PARP10 (0.67) PARP10SMN1; SMN2PRSS1ACRTMPRSS15
SCHEMBL70401 0.85 PARP10 (0.67) PARP10SMN1; SMN2PRSS1ACRTMPRSS15
SCHEMBL16675181 0.84 PARP10 (0.61) PARP10SMN1; SMN2PRSS1ACRTMPRSS15
SCHEMBL11132960 0.83 MAPT (0.54) PARP10SMN1; SMN2PRSS1ACRTMPRSS15
SCHEMBL28366245 0.83 POLB (0.62) PARP10NR4A1TNKSPARP15PARP14
SCHEMBL11208890 0.83 AKR1C3 (0.64) PARP10SMN1; SMN2KMT2AMAPTMEN1
Water SCHEMBL27930155 0.82 MAPT (0.52) PARP10SMN1; SMN2PRSS1ACRTMPRSS15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0115945-B1 SYNTHESIS OF HIGH MOLECULAR WEIGHT POLYBENZIMIDAZOLES CELANESE CORPORATION (US) 1988-11-30 — — EP claimed
EP-0115944-B1 PRODUCTION OF HIGH MOLECULAR WEIGHT POLYBENZIMIDAZOLES CELANESE CORPORATION (US) 1988-11-23 — — EP claimed
EP-0122735-B1 HIGH MOLECULAR WEIGHT POLYBENZIMIDAZOLE PRODUCTION CELANESE CORPORATION (US) 1987-11-25 — — EP claimed
US-4535144-A AMINOARYL ESTER REACTANT, TWO-STAGE MELT POLYMERIZATION CELANESE CORPORATION (US) 1985-08-13 — — US claimed
US-4506068-A FORMING A FOAMED PREPOLYMER ESTER-SUBSTITUTED ORTHIO-DIAMO AROMATIC COMPOUND CELANESE CORPORATION (US) 1985-03-19 — — US claimed
US-4485232-A Two stage melt production of high molecular weight polybenzimidazoles with phosphorous catalyst CELANESE CORPORATION (US) 1984-11-27 — — US claimed
EP-0122735-A2 High molecular weight polybenzimidazole production CELANESE CORPORATION (US) 1984-10-24 — — EP claimed
EP-0115945-A2 Synthesis of high molecular weight polybenzimidazoles CELANESE CORPORATION (US) 1984-08-15 — — EP claimed
EP-0115944-A2 Production of high molecular weight polybenzimidazoles CELANESE CORPORATION (US) 1984-08-15 — — EP claimed
US-11569512-B2 High-performance membrane electrode unit and the use thereof in fuel cells BASF FUEL CELL GMBH (DE) 2023-01-31 — — US disclosed
EP-2443175-B1 COMPOSITION CONTAINING POLYAZOLE BASF SE (DE) 2014-11-19 — — EP disclosed
US-8722279-B2 Polyazole-containing composition BASF SE (DE) 2014-05-13 — — US disclosed
US-8669296-B2 Method for the production of a high-molecular polyazol BASF SE (DE) 2014-03-11 — — US disclosed
US-8177863-B2 Method for the production of membrane/electrode units BASF FUEL CELL GMBH (DE) 2012-05-15 — — US disclosed
US-4506068-A FORMING A FOAMED PREPOLYMER ESTER-SUBSTITUTED ORTHIO-DIAMO AROMATIC COMPOUND CELANESE CORPORATION (US) 1985-03-19 — — US disclosed
US-4485232-A Two stage melt production of high molecular weight polybenzimidazoles with phosphorous catalyst CELANESE CORPORATION (US) 1984-11-27 — — US disclosed
EP-0122735-A2 High molecular weight polybenzimidazole production CELANESE CORPORATION (US) 1984-10-24 — — EP disclosed
EP-0115945-A2 Synthesis of high molecular weight polybenzimidazoles CELANESE CORPORATION (US) 1984-08-15 — — EP disclosed
US-4463167-A Two stage high molecular weight polybenzimidazole production with phosphorus containing catalyst CELANESE CORPORATION (US) 1984-07-31 — — US disclosed
US-4452972-A Production of high molecular weight polybenzimidazole with aryl phosphonic acid or aryl phosphinic acid catalyst CELANESE CORPORATION (US) 1984-06-05 — — US disclosed
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