Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 14/20 | 0.79 |
| ▸ | CASP1 | P29466 | 8/20 | 0.79 |
| ▸ | CASP9 | P55211 | 4/20 | 0.79 |
| ▸ | CASP7 | P55210 | 9/20 | 0.71 |
| ▸ | CASP4 | P49662 | 3/20 | 0.55 |
| ▸ | CASP5 | P51878 | 2/20 | 0.55 |
| ▸ | CASP6 | P55212 | 2/20 | 0.55 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.55 |
| ▸ | CASP10 | Q92851 | 2/20 | 0.55 |
| ▸ | APC | P25054 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19015930 | 0.95 | CASP3 (0.78) | CASP3CASP1CASP9CASP7CASP4 | |
| SCHEMBL18782018 | 0.90 | CASP3 (0.69) | CASP3CASP1CASP9CASP7CASP4 | |
| SCHEMBL18472477 | 0.90 | CASP3 (0.69) | CASP3CASP1CASP9CASP7CASP4 | |
| SCHEMBL18471954 | 0.88 | CASP3 (0.69) | CASP3CASP1CASP9CASP7CASP4 | |
| SCHEMBL7884997 | 0.88 | CASP3 (1.00) | CASP3CASP1CASP9CASP7CASP4 | |
| SCHEMBL20052448 | 0.86 | CASP3 (0.74) | CASP3CASP1CASP9CASP7CASP4 | |
| SCHEMBL16376154 | 0.83 | CASP3 (1.00) | CASP3CASP1CASP9CASP7CASP4 | |
| SCHEMBL18782016 | 0.83 | CASP3 (1.00) | CASP3CASP1CASP9CASP7CASP4 | |
| SCHEMBL9961951 | 0.83 | CASP3 (1.00) | CASP3CASP1CASP9CASP7CASP4 | |
| SCHEMBL19015966 | 0.83 | CASP3 (0.55) | CASP3CASP1CASP9CASP7CASP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2288615-B1 | SELECTIVE CASPASE INHIBITORS AND USES THEREOF | GENESIS TECH LTD (BB) | 2017-06-21 | — | — | EP | disclosed |