Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 9/20 | 0.74 |
| ▸ | CASP7 | P55210 | 6/20 | 0.74 |
| ▸ | CASP1 | P29466 | 5/20 | 0.74 |
| ▸ | CASP9 | P55211 | 4/20 | 0.71 |
| ▸ | CASP4 | P49662 | 2/20 | 0.71 |
| ▸ | CASP5 | P51878 | 2/20 | 0.71 |
| ▸ | CASP6 | P55212 | 2/20 | 0.71 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.71 |
| ▸ | CASP10 | Q92851 | 2/20 | 0.71 |
| ▸ | NMBR | P28336 | 2/20 | 0.56 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | CCKAR | P32238 | 3/20 | 0.51 |
| ▸ | CCKBR | P32239 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18782323 | 0.91 | CASP3 (0.72) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL15462653 | 0.89 | CASP3 (0.92) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL19015752 | 0.86 | CASP3 (0.79) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL20609292 | 0.85 | CASP3 (1.00) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL12829768 | 0.85 | CASP3 (1.00) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL18471462 | 0.85 | CASP3 (0.86) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL18471954 | 0.83 | CASP3 (0.69) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL16376111 | 0.83 | CASP3 (0.92) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL20052456 | 0.82 | CASP3 (0.62) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL19015930 | 0.81 | CASP3 (0.78) | CASP3CASP7CASP1CASP9CASP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944674-B2 | Selective cysteine protease inhibitors and uses thereof | GENESIS TECHNOLOGIES LIMITED (BB) | 2018-04-17 | — | — | US | disclosed |