Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 9/20 | 0.57 |
| ▸ | CASP1 | P29466 | 12/20 | 0.55 |
| ▸ | CASP7 | P55210 | 8/20 | 0.55 |
| ▸ | CASP9 | P55211 | 3/20 | 0.39 |
| ▸ | CASP4 | P49662 | 3/20 | 0.39 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.39 |
| ▸ | CASP10 | Q92851 | 2/20 | 0.39 |
| ▸ | CASP2 | P42575 | 1/20 | 0.39 |
| ▸ | CASP5 | P51878 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 4/20 | 0.38 |
| ▸ | CTSB | P07858 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19015946 | 0.97 | CASP3 (0.60) | CASP3CASP1CASP7CTSLCTSB | |
| SCHEMBL19015901 | 0.96 | CASP3 (0.59) | CASP3CASP1CASP7CASP9CASP4 | |
| SCHEMBL19015925 | 0.91 | CASP3 (0.53) | CASP3CASP1CASP7CASP9CASP4 | |
| SCHEMBL19015829 | 0.89 | CASP3 (0.60) | CASP3CASP1CASP7CASP9CASP4 | |
| SCHEMBL19015902 | 0.86 | CASP3 (0.56) | CASP3CASP1CASP7CASP9CASP4 | |
| SCHEMBL18781767 | 0.85 | CASP3 (0.78) | CASP3CASP1CASP7CASP9CASP4 | |
| SCHEMBL19015847 | 0.84 | CASP3 (0.45) | CASP3CASP1CASP7 | |
| SCHEMBL18781763 | 0.83 | CASP3 (0.77) | CASP3CASP1CASP7CASP9CASP4 | |
| SCHEMBL7879121 | 0.83 | CASP3 (0.77) | CASP3CASP1CASP7CASP9CASP4 | |
| SCHEMBL19015831 | 0.82 | CASP3 (0.43) | CASP3CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2288615-B1 | SELECTIVE CASPASE INHIBITORS AND USES THEREOF | GENESIS TECH LTD (BB) | 2017-06-21 | — | — | EP | disclosed |