Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 3/20 | 0.60 |
| ▸ | CASP7 | P55210 | 2/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 13/20 | 0.39 |
| ▸ | CTSB | P07858 | 10/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19015809 | 0.97 | CASP3 (0.57) | CASP3CASP7CASP1CTSLCTSB | |
| SCHEMBL19015925 | 0.94 | CASP3 (0.53) | CASP3CASP7CASP1CTSLCTSB | |
| SCHEMBL19015901 | 0.93 | CASP3 (0.59) | CASP3CASP7CASP1CTSLCTSB | |
| SCHEMBL18781767 | 0.88 | CASP3 (0.78) | CASP3CASP7CASP1 | |
| SCHEMBL19015847 | 0.86 | CASP3 (0.45) | CASP3CASP7CASP1 | |
| SCHEMBL19015829 | 0.85 | CASP3 (0.60) | CASP3CASP7CASP1CTSLCTSB | |
| SCHEMBL19015831 | 0.84 | CASP3 (0.43) | CASP3CASP7CASP1 | |
| SCHEMBL7887042 | 0.84 | CASP3 (0.62) | CASP3CASP7CASP1CTSLCTSB | |
| SCHEMBL19015902 | 0.83 | CASP3 (0.56) | CASP3CASP7CASP1CTSLCTSB | |
| SCHEMBL7890373 | 0.82 | CASP3 (0.59) | CASP3CASP7CASP1CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2288615-B1 | SELECTIVE CASPASE INHIBITORS AND USES THEREOF | GENESIS TECH LTD (BB) | 2017-06-21 | — | — | EP | disclosed |