Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | CTSS | P25774 | 5/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19015741 | 0.82 | CA2 (0.34) | ABCB1 | |
| SCHEMBL19015915 | 0.81 | CYP2D6 (0.44) | CTSKCYP2D6 | |
| SCHEMBL7886129 | 0.79 | ABCB1 (0.46) | CTSKPPARACTSSATMABCB1 | |
| SCHEMBL19015969 | 0.79 | ABCB1 (0.46) | CTSKPPARACTSSATMABCB1 | |
| SCHEMBL19015936 | 0.76 | CTSK (0.40) | CTSKCYP2D6 | |
| SCHEMBL7884932 | 0.73 | CYP2D6 (0.45) | CTSKCYP2D6 | |
| SCHEMBL9961219 | 0.72 | CYP2D6 (0.44) | CTSKCYP2D6 | |
| SCHEMBL9961231 | 0.71 | CYP2D6 (0.46) | CTSKCYP2D6 | |
| SCHEMBL19015933 | 0.70 | ABCB1 (0.44) | CTSKPPARACTSSATMABCB1 | |
| SCHEMBL7887501 | 0.70 | ABCB1 (0.44) | CTSKPPARACTSSATMABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2288615-B1 | SELECTIVE CASPASE INHIBITORS AND USES THEREOF | GENESIS TECH LTD (BB) | 2017-06-21 | — | — | EP | disclosed |