Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 12/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19015818 | 0.81 | USP2 (0.38) | CTSKCTSLCTSBCTSDCTSS | |
| SCHEMBL8364667 | 0.80 | CYP2D6 (0.46) | CTSKCYP2D6 | |
| SCHEMBL7882951 | 0.78 | CASP3 (0.47) | CTSKCTSLCTSBCYP2D6CTSD | |
| SCHEMBL19015811 | 0.73 | CTSK (0.42) | CTSKCYP2D6 | |
| SCHEMBL7885775 | 0.70 | CTSK (0.49) | CTSKCYP2D6 | |
| SCHEMBL28907829 | 0.69 | CTSK (0.62) | CTSKCYP2D6 | |
| SCHEMBL3498624 | 0.69 | CTSK (0.62) | CTSKCYP2D6 | |
| SCHEMBL1261148 | 0.69 | CTSK (0.62) | CTSKCYP2D6 | |
| SCHEMBL19015874 | 0.69 | CYP2D6 (0.48) | CTSKCYP2D6 | |
| SCHEMBL7351268 | 0.68 | CYP2D6 (0.47) | CTSKCYP2D6CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2288615-B1 | SELECTIVE CASPASE INHIBITORS AND USES THEREOF | GENESIS TECH LTD (BB) | 2017-06-21 | — | — | EP | disclosed |