Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | FPR1 | P21462 | 3/20 | 0.33 |
| ▸ | FPR2 | P25090 | 3/20 | 0.33 |
| ▸ | KLK7 | P49862 | 1/20 | 0.33 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19015919 | 0.80 | CASP3 (0.39) | CASP3CASP1CASP7CACNA1BMETAP1 | |
| SCHEMBL19015819 | 0.72 | CASP3 (0.44) | CASP3CASP1CASP7USP2 | |
| SCHEMBL24016806 | 0.72 | KLK5 (0.51) | MMP3KLK5 | |
| SCHEMBL27020331 | 0.70 | EPHX2 (0.37) | CACNA1BMETAP1EPHX2KLK5 | |
| SCHEMBL1916259 | 0.70 | PLA2G10 (0.37) | EPHX2GRM7 | |
| SCHEMBL1916264 | 0.70 | PLA2G10 (0.37) | EPHX2GRM7 | |
| SCHEMBL27709304 | 0.68 | HDAC3 (0.42) | CYP2D6 | |
| SCHEMBL13925605 | 0.68 | CYP2D6 (0.40) | CYP2D6 | |
| SCHEMBL28211811 | 0.68 | HDAC3 (0.42) | CYP2D6 | |
| SCHEMBL3499495 | 0.67 | CYP2D6 (0.39) | CACNA1BKLK5CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2288615-B1 | SELECTIVE CASPASE INHIBITORS AND USES THEREOF | GENESIS TECH LTD (BB) | 2017-06-21 | — | — | EP | disclosed |