Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 3/20 | 0.39 |
| ▸ | CASP1 | P29466 | 7/20 | 0.36 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 3/20 | 0.33 |
| ▸ | REN | P00797 | 2/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19015914 | 0.86 | CASP3 (0.52) | CASP3CASP1CASP7 | |
| SCHEMBL7888466 | 0.86 | CASP3 (0.52) | CASP3CASP1CASP7 | |
| SCHEMBL19015892 | 0.80 | CASP3 (0.37) | CASP3CASP1CASP7USP2CACNA1B | |
| SCHEMBL7890373 | 0.79 | CASP3 (0.59) | CASP3CASP1CASP7REN | |
| SCHEMBL19015896 | 0.78 | SMN1; SMN2 (0.39) | SMN1; SMN2 | |
| SCHEMBL19015773 | 0.77 | CASP3 (0.37) | CASP3CASP1CASP7 | |
| SCHEMBL7877666 | 0.75 | CASP3 (0.54) | CASP3CASP1CASP7 | |
| SCHEMBL7887265 | 0.74 | CASP3 (0.61) | CASP3CASP1CASP7 | |
| SCHEMBL9961904 | 0.74 | CASP3 (0.61) | CASP3CASP1CASP7 | |
| SCHEMBL18471338 | 0.74 | CASP3 (0.61) | CASP3CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2288615-B1 | SELECTIVE CASPASE INHIBITORS AND USES THEREOF | GENESIS TECH LTD (BB) | 2017-06-21 | — | — | EP | disclosed |