Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19016242 | 0.85 | ITGB3 (0.41) | ALDH1A1ITGB3ITGAVHDAC3HDAC4 | |
| SCHEMBL15362287 | 0.85 | ITGB3 (0.41) | ALDH1A1ITGB3ITGAVHDAC3HDAC4 | |
| SCHEMBL10036356 | 0.83 | ITGB3 (0.41) | ALDH1A1ITGB3ITGAVHDAC3HDAC4 | |
| SCHEMBL23817079 | 0.82 | ITGB3 (0.39) | ALDH1A1ITGB3ITGAVHDAC3HDAC4 | |
| SCHEMBL22354532 | 0.82 | ITGB3 (0.39) | ALDH1A1ITGB3ITGAVHDAC3HDAC4 | |
| SCHEMBL16602341 | 0.82 | ITGB3 (0.46) | ALDH1A1ITGB3ITGAVHDAC3HDAC4 | |
| SCHEMBL22779176 | 0.82 | HDAC3 (0.43) | ALDH1A1ITGB3ITGAVHDAC3HDAC4 | |
| SCHEMBL16307671 | 0.81 | TP53 (0.48) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL24588450 | 0.81 | HDAC3 (0.46) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL24588451 | 0.81 | HDAC3 (0.46) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102613-A1 | SELECTIVE GLUCAGON RECEPTOR AGONISTS COMPRISING A CHELATING MOIETY FOR IMAGING PURPOSES | SANOFI (FR) | 2017-06-22 | — | — | WO | disclosed |