Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21208105 | 0.91 | SMN1; SMN2 (0.45) | TP53SMN1; SMN2HDAC3HDAC4HDAC1 | |
| SCHEMBL18557387 | 0.85 | SMN1; SMN2 (0.46) | TP53SMN1; SMN2HDAC3HDAC4HDAC1 | |
| SCHEMBL21648779 | 0.83 | HDAC3 (0.47) | TP53SMN1; SMN2HDAC3HDAC4HDAC1 | |
| SCHEMBL18557292 | 0.82 | LMNA (0.43) | SMN1; SMN2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL24588450 | 0.81 | HDAC3 (0.46) | SMN1; SMN2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL19016233 | 0.81 | ALDH1A1 (0.44) | TP53SMN1; SMN2HDAC3HDAC4HDAC1 | |
| SCHEMBL24588451 | 0.81 | HDAC3 (0.46) | SMN1; SMN2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL21954002 | 0.81 | MEN1 (0.43) | SMN1; SMN2KMT2AMEN1CYP2C19ALDH1A1 | |
| SCHEMBL16867171 | 0.80 | HDAC3 (0.39) | TP53SMN1; SMN2HDAC3HDAC4HDAC1 | |
| SCHEMBL16867169 | 0.80 | HDAC3 (0.39) | TP53SMN1; SMN2HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9579367-B2 | C-terminally tethered amino acids and their fibrinolytic therapeutic uses | CANADIAN BLOOD SERVICES (CA) | 2017-02-28 | — | — | US | disclosed |
| US-9579367-B2 | C-terminally tethered amino acids and their fibrinolytic therapeutic uses | CANADIAN BLOOD SERVICES (CA) | 2017-02-28 | — | — | US | disclosed |
| US-20140369992-A1 | C-Terminally Tethered Amino Acids and Their Fibrinolytic Therapeutic Uses | CANADIAN BLOOD SERVICES (CA) | 2014-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140369992-A1 | C-Terminally Tethered Amino Acids and Their Fibrinolytic Therapeutic Uses | HABP2, FGB, PROC | TP53 2938/4885SMN1; SMN2 4220/4885HDAC3 1825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.