SCHEMBL1901773

SCHEMBL1901773

CCN(CCOc1cnn(Cc2ccccc2)c(=O)c1)C(=O)O.O=C(O)CNC(=O)CC(F)=C(F)F

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 9/20 0.41
KMT2A Q03164 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ALDH1A1 P00352 3/20 0.35
TP53 P04637 2/20 0.35
KDM4E B2RXH2 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
PTGS1 P23219 1/20 0.35
LMNA P02545 2/20 0.35
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
GCGR P47871 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL396952 0.86 MCHR1 (0.49) MCHR1ALDH1A1PTGS1LMNAMAPK1
SCHEMBL5405257 0.85 MCHR1 (0.40) MCHR1ALDH1A1TP53KDM4ENPSR1
SCHEMBL6598680 0.75 PARP1 (0.34) KMT2AKDM4ENPSR1
SCHEMBL3128916 0.71 PTGS1 (0.46) MCHR1ALDH1A1PTGS1LMNASMN1; SMN2
SCHEMBL9572963 0.70 L3MBTL1 (0.48) MCHR1KMT2ATDP1ALDH1A1TP53
SCHEMBL6575798 0.69 MCHR1 (0.35) MCHR1ALDH1A1PTGS1LMNAMAPK1
SCHEMBL8783937 0.69 PTGS1 (0.47) MCHR1PTGS1
SCHEMBL9520130 0.68 MCHR1 (0.43) MCHR1KMT2ATDP1PTGS1SMN1; SMN2
SCHEMBL8783353 0.67 PTGS1 (0.45) MCHR1ALDH1A1PTGS1
SCHEMBL3602607 0.67 PTGS1 (0.46) MCHR1ALDH1A1PTGS1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2316268-A1 Fungicidal combinations comprising trifloxystrobin Bayer CropScience AG (DE) 2011-05-04 EP disclosed
EP-1448549-A1 DELTA1-PYRROLINES Bayer CropScience AG (DE) 2004-08-25 EP disclosed
EP-1366043-A1 2-HETEROARYL-3,4-DIHYDRO-2H-PYRROLE DERIVATIVES AND THE USE THEREOF AS PESTICIDES Bayer CropScience AG (DE) 2003-12-03 EP disclosed
WO-2003040130-A1 $g(D)1-PYRROLINES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2003-05-15 WO disclosed
WO-2002064588-A1 2-HETEROARYL-3,4-DIHYDRO-2H-PYRROLE DERIVATIVES AND THE USE THEREOF AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2002-08-22 WO disclosed