Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 17/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiacloprid SCHEMBL6618093 | 0.86 | CHRNA7 (0.43) | SMN1; SMN2 | |
| SCHEMBL396952 | 0.80 | MCHR1 (0.49) | MCHR1PTGS1ALDH1A1LMNAMAPK1 | |
| Thiacloprid SCHEMBL6631236 | 0.80 | MEN1 (0.36) | — | |
| SCHEMBL6262185 | 0.79 | PARP1 (0.33) | — | |
| Thiacloprid SCHEMBL6056083 | 0.71 | CHRNA7 (0.41) | SMN1; SMN2 | |
| SCHEMBL1901773 | 0.69 | MCHR1 (0.41) | MCHR1PTGS1ALDH1A1LMNAMAPK1 | |
| SCHEMBL8783937 | 0.64 | PTGS1 (0.47) | MCHR1PTGS1 | |
| SCHEMBL396950 | 0.63 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL8783353 | 0.63 | PTGS1 (0.45) | MCHR1PTGS1ALDH1A1 | |
| SCHEMBL3602607 | 0.63 | PTGS1 (0.46) | MCHR1PTGS1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412334-A1 | PYRAZOLINE DERIVATIVES AND THEIR USE AS PESTICIDES | Bayer CropScience AG (DE) | 2004-04-28 | — | — | EP | disclosed |
| WO-2003029213-A9 | SPIROCYCLIC 3-PHENYL-3-SUBSTITUTED 4-KETOLACTAMS AND 4-KETOLACTONES | BAYER CROPSCIENCE AG (DE) | 2003-11-13 | — | — | WO | disclosed |
| WO-2003010148-A1 | PYRAZOLINE DERIVATIVES AND THEIR USE AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2003-02-06 | — | — | WO | disclosed |