Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 7/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7698552 | 0.88 | PDE4A (0.70) | PDE4APDE4BPDE4DPDE3BPDE3A | |
| SCHEMBL19017950 | 0.86 | PDE4A (0.42) | PDE4APDE4BPDE4DPDE3BPDE3A | |
| SCHEMBL19017830 | 0.85 | PDE4A (0.57) | PDE4APDE4BPDE4DPDE3BPDE3A | |
| SCHEMBL19018021 | 0.84 | PDE4A (0.41) | PDE4APDE4BPDE4DPDE3BPDE3A | |
| SCHEMBL14947099 | 0.81 | PDE4A (0.71) | PDE4APDE4BPDE4DPDE3BPDE3A | |
| SCHEMBL18857624 | 0.76 | PDE4A (0.44) | PDE4APDE4BPDE4DPDE3BPDE3A | |
| SCHEMBL4565777 | 0.76 | PDE4A (0.78) | PDE4APDE4BPDE4DPDE3BPDE3A | |
| SCHEMBL18853957 | 0.73 | PDE4A (0.42) | PDE4APDE4BPDE4DPDE3BPDE3A | |
| SCHEMBL18857435 | 0.73 | PDE4A (0.48) | PDE4APDE4BPDE4DPDE3BPDE3A | |
| SCHEMBL7700350 | 0.72 | PDE4A (0.86) | PDE4APDE4BPDE4DPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017103058-A1 | METHODS FOR THE PREPARATION OF 1,3-BENZODIOXOLE HETEROCYCLIC COMPOUNDS | LEO PHARMA A/S (DK) | 2017-06-22 | — | — | WO | disclosed |