Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 8/20 | 0.70 |
| ▸ | PDE4D | Q08499 | 12/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.53 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.53 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19018024 | 0.88 | PDE4A (0.55) | PDE4APDE4DPDE4BPDE3BPDE3A | |
| SCHEMBL14947099 | 0.88 | PDE4A (0.71) | PDE4APDE4DPDE4BPDE3BPDE3A | |
| SCHEMBL4565777 | 0.87 | PDE4A (0.78) | PDE4APDE4DPDE4BPDE3BPDE3A | |
| SCHEMBL7700350 | 0.83 | PDE4A (0.86) | PDE4APDE4DPDE4BPDE3BPDE3A | |
| SCHEMBL14947100 | 0.82 | PDE4A (1.00) | PDE4APDE4DPDE4BPDE3BPDE3A | |
| SCHEMBL19017830 | 0.78 | PDE4A (0.57) | PDE4APDE4DPDE4BPDE3BPDE3A | |
| SCHEMBL434451 | 0.78 | PDE4A (0.66) | PDE4APDE4DPDE4BPDE3BPDE3A | |
| SCHEMBL5751710 | 0.77 | PDE4A (0.65) | PDE4APDE4DPDE4BPDE3BPDE3A | |
| SCHEMBL6836821 | 0.77 | PDE4A (0.65) | PDE4APDE4DPDE4BPDE3BPDE3A | |
| SCHEMBL14456335 | 0.77 | PDE4A (0.59) | PDE4APDE4DPDE4BPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011160632-A1 | BENZODIOXOLE OR BENZODIOXEPINE HETEROCYCLIC COMPOUNDS PHOSPHODIESTERASE INHIBITORS | LEO PHARMA A/S (DK) | 2011-12-29 | — | — | WO | disclosed |