Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 15/20 | 0.52 |
| ▸ | ITGAV | P06756 | 10/20 | 0.52 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.52 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.50 |
| ▸ | ITGB5 | P18084 | 4/20 | 0.49 |
| ▸ | CD2 | P06729 | 1/20 | 0.48 |
| ▸ | CD58 | P19256 | 1/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.47 |
| ▸ | CD40 | P25942 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24253222 | 0.86 | ITGB3 (0.58) | ITGB3ITGAVITGB1ITGA5ITGA2B | |
| SCHEMBL24253223 | 0.86 | ITGB3 (0.58) | ITGB3ITGAVITGB1ITGA5ITGA2B | |
| SCHEMBL15160075 | 0.86 | ITGB3 (0.50) | ITGB3ITGAVITGB1ITGA5ITGA2B | |
| SCHEMBL23823920 | 0.85 | CACNA1B (0.53) | ITGB3ITGAVITGB1ITGA5ITGA2B | |
| SCHEMBL23824132 | 0.84 | CACNA1B (0.51) | ITGB3ITGAVITGB1ITGA5ITGA2B | |
| SCHEMBL23824184 | 0.84 | CACNA1B (0.51) | ITGB3ITGAVITGB1ITGA5ITGA2B | |
| SCHEMBL10049951 | 0.83 | ITGB3 (0.60) | ITGB3ITGAVITGA5ITGA2BITGB5 | |
| SCHEMBL15308349 | 0.83 | ITGB3 (0.53) | ITGB3ITGAVITGB1ITGA5ITGA2B | |
| SCHEMBL23839922 | 0.83 | ITGB3 (0.56) | ITGB3ITGAVITGB1ITGA5ITGA2B | |
| SCHEMBL24454392 | 0.83 | ITGB3 (0.56) | ITGB3ITGAVITGB1ITGA5ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017106253-A1 | CONFORMATIONALLY STRAINED TRANS-CYCLOALKENES FOR RADIOLABELING | FOX JOSEPH (US) | 2017-06-22 | — | — | WO | disclosed |