Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.51 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.48 |
| ▸ | KDM4A | O75164 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.46 |
| ▸ | ITGAV | P06756 | 2/20 | 0.46 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.46 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.46 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.45 |
| ▸ | CTSG | P08311 | 2/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.44 |
| ▸ | CD40 | P25942 | 1/20 | 0.43 |
| ▸ | KRAS | P01116 | 1/20 | 0.43 |
| ▸ | NNMT | P40261 | 1/20 | 0.43 |
| ▸ | CD2 | P06729 | 1/20 | 0.43 |
| ▸ | CD58 | P19256 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | BAD | Q92934 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23824132 | 1.00 | CACNA1B (0.51) | CACNA1BGNAI1KDM4AITGB3ITGB1 | |
| SCHEMBL23823920 | 0.87 | CACNA1B (0.53) | CACNA1BKDM4AITGB3ITGB1ITGAV | |
| SCHEMBL7746029 | 0.87 | ITGB3 (0.56) | CACNA1BGNAI1KDM4AITGB3ITGB1 | |
| SCHEMBL15308347 | 0.87 | ITGB3 (0.56) | CACNA1BGNAI1KDM4AITGB3ITGB1 | |
| SCHEMBL19018807 | 0.87 | ITGB3 (0.56) | CACNA1BGNAI1KDM4AITGB3ITGB1 | |
| SCHEMBL23839922 | 0.87 | ITGB3 (0.56) | CACNA1BGNAI1KDM4AITGB3ITGB1 | |
| SCHEMBL24454392 | 0.87 | ITGB3 (0.56) | CACNA1BGNAI1KDM4AITGB3ITGB1 | |
| SCHEMBL19018674 | 0.84 | ITGB3 (0.52) | CACNA1BITGB3ITGB1ITGAVITGA5 | |
| SCHEMBL22970200 | 0.84 | ITGB3 (0.56) | ITGB3ITGB1ITGAVITGA5ITGB5 | |
| SCHEMBL21577745 | 0.84 | ITGB3 (0.56) | ITGB3ITGB1ITGAVITGA5ITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210283278-A1 | CHIRAL CYCLEN COMPOUNDS AND THEIR USES | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2021-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210283278-A1 | CHIRAL CYCLEN COMPOUNDS AND THEIR USES | DCTN3, DCTN1, CDK3 | CACNA1B 191/4885GNAI1 1369/4885KDM4A 1052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.