SCHEMBL1901874

SCHEMBL1901874

Cc1[nH]nc(C(F)(F)F)c1C(=O)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.49
HSD17B10 Q99714 1/20 0.49
CCNA2 P20248 1/20 0.40
CDK2 P24941 1/20 0.40
CCNA1 P78396 1/20 0.40
ALDH1A1 P00352 2/20 0.40
GAA P10253 2/20 0.40
POLB P06746 2/20 0.40
KMT2A Q03164 2/20 0.40
MAPT P10636 2/20 0.40
KDM4E B2RXH2 1/20 0.40
P2RX7 Q99572 1/20 0.38
CES1 P23141 1/20 0.38
GLA P06280 1/20 0.38
HPGD P15428 1/20 0.38
JUN P05412 1/20 0.37
NFKB1 P19838 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
NPC1 O15118 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14822491 0.80 KDM4E (0.45) POLBKMT2AMAPTKDM4EP2RX7
SCHEMBL28869489 0.80 AURKA (0.47) CCNA2CDK2CCNA1ALDH1A1GAA
Hydrochloric Acid SCHEMBL28469900 0.79 AURKA (0.46) CCNA2CDK2CCNA1ALDH1A1GAA
SCHEMBL3637493 0.78 PDE4D (0.49) HTTCCNA2CDK2CCNA1ALDH1A1
SCHEMBL11307153 0.77 ALDH1A1 (0.45) HTTCCNA2CDK2CCNA1ALDH1A1
SCHEMBL9830631 0.76 KMT2A (0.50) HTTCCNA2CDK2CCNA1ALDH1A1
Sulfuric Acid SCHEMBL28476950 0.76 AURKA (0.43) CCNA2CDK2CCNA1ALDH1A1GAA
SCHEMBL6257457 0.75 KDM4E (0.44) GAAPOLBKMT2AMAPTKDM4E
SCHEMBL14044117 0.71 HCAR2 (0.61) CCNA2CDK2CCNA1ALDH1A1GAA
SCHEMBL28349789 0.69 HTT (0.46) HTTHSD17B10ALDH1A1GAAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2494648-A1 LITHIUM SULFUR BATTERY Solvay Fluor GmbH (DE) 2012-09-05 EP disclosed
WO-2011051275-A1 LITHIUM SULFUR BATTERY SOLVAY FLUOR GMBH (DE) 2011-05-05 WO disclosed