Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.56 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.56 |
| ▸ | ITGAV | P06756 | 3/20 | 0.49 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.49 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.49 |
| ▸ | CTSG | P08311 | 1/20 | 0.49 |
| ▸ | MC4R | P32245 | 4/20 | 0.49 |
| ▸ | MC5R | P33032 | 4/20 | 0.49 |
| ▸ | MC3R | P41968 | 4/20 | 0.49 |
| ▸ | MC1R | Q01726 | 4/20 | 0.49 |
| ▸ | CD2 | P06729 | 1/20 | 0.48 |
| ▸ | CD58 | P19256 | 1/20 | 0.48 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.48 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.48 |
| ▸ | KDM4A | O75164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7746029 | 1.00 | ITGB3 (0.56) | ITGB3ITGA2BCACNA1BITGAVITGB5 | |
| SCHEMBL15308347 | 1.00 | ITGB3 (0.56) | ITGB3ITGA2BCACNA1BITGAVITGB5 | |
| SCHEMBL24454392 | 1.00 | ITGB3 (0.56) | ITGB3ITGA2BCACNA1BITGAVITGB5 | |
| SCHEMBL23839922 | 1.00 | ITGB3 (0.56) | ITGB3ITGA2BCACNA1BITGAVITGB5 | |
| SCHEMBL29393726 | 0.96 | ITGB3 (0.59) | ITGB3ITGA2BCACNA1BITGAVITGB5 | |
| SCHEMBL7743533 | 0.93 | ITGB3 (0.55) | ITGB3ITGA2BITGAVITGB5ITGB1 | |
| SCHEMBL7743878 | 0.93 | ITGB3 (0.55) | ITGB3ITGA2BITGAVITGB5ITGB1 | |
| SCHEMBL19605481 | 0.93 | ITGB3 (0.55) | ITGB3ITGA2BITGAVITGB5ITGB1 | |
| SCHEMBL21475019 | 0.93 | ITGB3 (0.55) | ITGB3ITGA2BITGAVITGB5ITGB1 | |
| SCHEMBL13107808 | 0.93 | ITGB3 (0.55) | ITGB3ITGA2BITGAVITGB5ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017106253-A1 | CONFORMATIONALLY STRAINED TRANS-CYCLOALKENES FOR RADIOLABELING | FOX JOSEPH (US) | 2017-06-22 | — | — | WO | disclosed |