SCHEMBL19019192

SCHEMBL19019192

C/C=C(C#N)\C(C#N)=C/C

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.35
KMT2A Q03164 2/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CYP2C9 P11712 1/20 0.34
ALDH1A1 P00352 2/20 0.31
MEN1 O00255 1/20 0.31
MCL1 Q07820 1/20 0.31
CISD1 Q9NZ45 1/20 0.31
KDM4E B2RXH2 1/20 0.31
SLC16A3 O15427 1/20 0.31
CYP3A4 P08684 1/20 0.31
HPGD P15428 1/20 0.31
SLC16A1 P53985 1/20 0.31
GPR35 Q9HC97 1/20 0.31
EGFR P00533 1/20 0.31
LMNA P02545 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11856272 1.00 TDP1 (0.35) TDP1KMT2ARAB9ASMN1; SMN2CYP2C9
SCHEMBL11856278 1.00 TDP1 (0.35) TDP1KMT2ARAB9ASMN1; SMN2CYP2C9
SCHEMBL22991020 0.80 MCL1 (0.32) MCL1
SCHEMBL19019704 0.80 TDP1 (0.30) TDP1
SCHEMBL13821259 0.80 CYP2C9 (0.31) TDP1CYP2C9KDM4E
SCHEMBL11809406 0.79
SCHEMBL26755 0.79
SCHEMBL13891834 0.79
SCHEMBL1959929 0.79
SCHEMBL11809392 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11795357-B2 Poly(etherimide-phthalonitrile) adhesives and related methods THE BOEING COMPANY (US) 2023-10-24 US disclosed
US-20230063744-A1 Polymerizable Compositions Including a Phthalonitrile Resin and a Polyoxometalate, Articles, and Methods 3M INNOVATIVE PROPERTIES COMPANY 2023-03-02 US disclosed
US-20200299506-A1 BISPHENOL M DIPHTHALONITRILE ETHER RESIN BLENDS INCLUDING A FILLER, AND ARTICLES 3M INNOVATIVE PROPERTIES COMPANY 2020-09-24 US disclosed
US-10640598-B2 Resin blends of resorcinol diphthalonitrile ether with bisphenol M diphthalonitrile ether and/or bisphenol T diphthalonitrile ether 3M INNOVATIVE PROPERTIES COMPANY (US) 2020-05-05 US disclosed
US-10556991-B2 Benzoxazine and phthalonitrile resin blends 3M INNOVATIVE PROPERTIES COMPANY (US) 2020-02-11 US disclosed
US-20190055338-A1 RESIN BLENDS OF RESORCINOL DIPHTHALONITRILE ETHER WITH BISPHENOL M DIPHTHALONITRILE ETHER AND/OR BISPHENOL T DIPHTHALONITRILE ETHER 3M INNOVATIVE PROPERTIES COMPANY 2019-02-21 US disclosed
US-20190047946-A1 BISPHENOL M DIPHTHALONITRILE ETHER RESIN, BISPHENOL P DIPHTHALONITRILE ETHER RESIN, METHODS OF MAKING SAME, RESIN BLENDS, AND TWO COMPONENT SYSTEMS 3M INNOVATIVE PROPERTIES COMPANY 2019-02-14 US disclosed
WO-2017105890-A1 BENZOXAZINE AND PHTHALONITRILE RESIN BLENDS 3M INNOVATIVE PROPERTIES COMPANY (US) 2017-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10640598-B2 Resin blends of resorcinol diphthalonitrile ether with bisphenol M diphthalonitrile ether and/or bisphenol T diphthalonitrile ether WDR48, CUL4A, FHIT TDP1 3131/4885KMT2A 1368/4885RAB9A 2419/4885
US-20190055338-A1 RESIN BLENDS OF RESORCINOL DIPHTHALONITRILE ETHER WITH BISPHENOL M DIPHTHALONITRILE ETHER AND/OR BISPHENOL T DIPHTHALONITRILE ETHER WDR48, CUL4A, FHIT TDP1 3131/4885KMT2A 1368/4885RAB9A 2419/4885
US-20190047946-A1 BISPHENOL M DIPHTHALONITRILE ETHER RESIN, BISPHENOL P DIPHTHALONITRILE ETHER RESIN, METHODS OF MAKING SAME, RESIN BLENDS, AND TWO COMPONENT SYSTEMS PNN, POLN, RBBP4 TDP1 1791/4885KMT2A 1321/4885RAB9A 3870/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.