Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.52 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.47 |
| ▸ | CMA1 | P23946 | 4/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.45 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.43 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.43 |
| ▸ | REN | P00797 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22209394 | 0.93 | MALT1 (0.60) | MALT1EPHA2CMA1ELANEOPRM1 | |
| SCHEMBL18619548 | 0.93 | MALT1 (0.60) | MALT1EPHA2CMA1ELANEOPRM1 | |
| SCHEMBL22209365 | 0.88 | MALT1 (0.64) | MALT1EPHA2CMA1ELANE | |
| SCHEMBL18621052 | 0.88 | MALT1 (0.64) | MALT1EPHA2CMA1ELANE | |
| SCHEMBL22811073 | 0.88 | MALT1 (0.64) | MALT1EPHA2CMA1ELANE | |
| SCHEMBL18619572 | 0.88 | MALT1 (0.64) | MALT1EPHA2CMA1ELANE | |
| SCHEMBL22209378 | 0.86 | MALT1 (0.61) | MALT1EPHA2CMA1ELANEDPP4 | |
| SCHEMBL18619579 | 0.86 | MALT1 (0.61) | MALT1EPHA2CMA1ELANE | |
| SCHEMBL22209379 | 0.85 | MALT1 (0.61) | MALT1EPHA2CMA1ELANE | |
| SCHEMBL29872221 | 0.84 | DPP4 (0.52) | MALT1EPHA2OPRM1OPRK1NMUR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11884708-B2 | Stapled peptide inhibitors of nemo as potential anti-inflammatory and anti-cancer drugs | INSTITUT PASTEUR (FR) | 2024-01-30 | — | — | US | disclosed |
| US-20220025002-A1 | STAPLED PEPTIDE INHIBITORS OF NEMO AS POTENTIAL ANTI-INFLAMMATORY AND ANTI-CANCER DRUGS | INSTITUT PASTEUR (FR) | 2022-01-27 | — | — | US | disclosed |
| US-11149070-B2 | Stapled peptide inhibitors of NEMO as potential anti-inflammatory and anti-cancer drugs | INSTITUT PASTEUR (FR) | 2021-10-19 | — | — | US | disclosed |
| EP-3394088-B1 | STAPLED PEPTIDE INHIBITORS OF NEMO AS POTENTIAL ANTI-INFLAMMATORY AND ANTI-CANCER DRUGS | PASTEUR INSTITUT (FR) | 2020-08-05 | — | — | EP | disclosed |
| EP-3184541-A1 | STAPLED PEPTIDE INHIBITORS OF NEMO AS POTENTIAL ANTI-INFLAMMATORY AND ANTI-CANCER DRUGS | Institut Pasteur (FR) | 2017-06-28 | — | — | EP | disclosed |