SCHEMBL1902007

SCHEMBL1902007

COC(=O)c1c(-c2ccccc2)cc(OC)c(OC)c1C(=O)OC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.52
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
PKM P14618 1/20 0.48
LMNA P02545 3/20 0.48
ALDH1A1 P00352 2/20 0.48
HPGD P15428 1/20 0.48
PRKCZ Q05513 1/20 0.48
GABRA1 P14867 1/20 0.47
GABRG2 P18507 1/20 0.47
GABRB3 P28472 1/20 0.47
GABRA5 P31644 1/20 0.47
GABRA3 P34903 1/20 0.47
TUBB4A P04350 5/20 0.46
TUBB P07437 5/20 0.46
TUBA3C P0DPH7 5/20 0.46
TUBA1B P68363 5/20 0.46
TUBA4A P68366 5/20 0.46
TUBB4B P68371 5/20 0.46
TUBB3 Q13509 5/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4778744 0.91 HTT (0.52) HTTMEN1KMT2APKMLMNA
SCHEMBL29248145 0.84 MEN1 (0.53) HTTMEN1KMT2APKMTUBB4A
SCHEMBL30901037 0.84 MEN1 (0.53) HTTMEN1KMT2APKMTUBB4A
SCHEMBL28792606 0.81 MEN1 (0.53) HTTMEN1KMT2APKMLMNA
SCHEMBL27717648 0.81 HTT (0.51) HTTMEN1KMT2APKMLMNA
SCHEMBL29672066 0.81 MEN1 (0.53) HTTMEN1KMT2APKMLMNA
SCHEMBL29034612 0.81 MEN1 (0.53) HTTMEN1KMT2APKMTUBB4A
SCHEMBL4115260 0.81 HTT (0.54) HTTMEN1KMT2ALMNAALDH1A1
SCHEMBL4776934 0.79 HTT (0.49) HTTMEN1KMT2APKMTUBB4A
SCHEMBL13228930 0.78 HTT (0.62) HTTMEN1KMT2ALMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8758822-B2 Method for manufacturing uniform size polymeric nanoparticles containing poorly soluble drugs KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2014-06-24 US claimed
US-20110171269-A1 METHOD FOR MANUFACTURING UNIFORM SIZE POLYMERIC NANOPARTICLES CONTAINING POORLY SOLUBLE DRUGS KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2011-07-14 US claimed
EP-2322470-A2 METHOD FOR MANUFACTURING UNIFORM SIZE POLYMERIC NANOPARTICLES CONTAINING POORLY SOLUBLE DRUGS Korea Research Institute of Bioscience and Biotechnology (KR) 2011-05-18 EP claimed
EP-3464563-B1 ALTERED ADHERENT STROMAL CELLS AND METHODS OF PRODUCING AND USING SAME PLURISTEM LTD (IL) 2021-07-28 EP disclosed
US-10851347-B2 Altered adherent stromal cells and methods of producing and using same PLURISTEM LTD. (IL) 2020-12-01 US disclosed
US-20200131481-A1 ALTERED ADHERENT STROMAL CELLS AND METHODS OF PRODUCING AND USING SAME PLURISTEM LTD. (IL) 2020-04-30 US disclosed
EP-3464563-A1 ALTERED ADHERENT STROMAL CELLS AND METHODS OF PRODUCING AND USING SAME Pluristem Ltd. (IL) 2019-04-10 EP disclosed
CN-109496236-A The adhering substrate cell of change and its generation and application method 普拉里斯坦有限公司 2019-03-19 CN disclosed
WO-2017212309-A1 ALTERED ADHERENT STROMAL CELLS AND METHODS OF PRODUCING AND USING SAME PLURISTEM LTD. (IL) 2017-12-14 WO disclosed
CN-102083742-B Method for preparing polymer nano-particles with uniform size and containing difficult-soluble medicine KOREA RES INST OF BIOSCIENCE 2014-08-20 CN disclosed
US-8758822-B2 Method for manufacturing uniform size polymeric nanoparticles containing poorly soluble drugs KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2014-06-24 US disclosed
US-20110171269-A1 METHOD FOR MANUFACTURING UNIFORM SIZE POLYMERIC NANOPARTICLES CONTAINING POORLY SOLUBLE DRUGS KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2011-07-14 US disclosed
CN-102083742-A Method for preparing polymer nano-particles with uniform size and containing difficult-soluble medicine KOREA RES INST OF BIOSCIENCE 2011-06-01 CN disclosed