Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 13/20 | 0.46 |
| ▸ | TUBB | P07437 | 13/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 13/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 13/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 13/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 13/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 13/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 13/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 13/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 13/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 13/20 | 0.46 |
| ▸ | TUBA1C | Q9BQE3 | 13/20 | 0.46 |
| ▸ | TUBB6 | Q9BUF5 | 13/20 | 0.46 |
| ▸ | TUBB2B | Q9BVA1 | 13/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 13/20 | 0.46 |
| ▸ | HK2 | P52789 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29034612 | 0.88 | MEN1 (0.53) | HTTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4778744 | 0.85 | HTT (0.52) | HTTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29248145 | 0.81 | MEN1 (0.53) | HTTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL30901037 | 0.81 | MEN1 (0.53) | HTTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1902007 | 0.79 | HTT (0.52) | HTTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28792606 | 0.78 | MEN1 (0.53) | HTTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29672066 | 0.78 | MEN1 (0.53) | HTTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28788991 | 0.78 | MEN1 (0.50) | HTTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL205626 | 0.77 | PDE4B (0.50) | HTTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6535979 | 0.76 | PDE4B (0.63) | HTTTUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940372-A1 | NOVEL AROMATIC COMPOUNDS AND THEIR USE IN MEDICAL APPLICATIONS | Revotar Biopharmaceuticals AG (DE) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007039113-A1 | NOVEL AROMATIC COMPOUNDS AND THEIR USE IN MEDICAL APPLICATIONS | REVOTAR BIOPHARMACEUTICALS AG (DE) | 2007-04-12 | — | — | WO | disclosed |