Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 10/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | SNCA | P37840 | 3/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19020196 | 1.00 | CDC25A (0.54) | CDC25AMEN1KMT2AAPPMAPT | |
| SCHEMBL19030731 | 1.00 | CDC25A (0.54) | CDC25AMEN1KMT2AAPPMAPT | |
| SCHEMBL19020193 | 0.84 | CDC25A (0.49) | CDC25AMEN1KMT2AAPPMAPT | |
| SCHEMBL19020194 | 0.84 | CDC25A (0.49) | CDC25AMEN1KMT2AAPPMAPT | |
| SCHEMBL18974999 | 0.80 | CES1 (0.67) | CDC25AMEN1KMT2AAPEX1 | |
| SCHEMBL29459522 | 0.78 | KMT2A (0.73) | MEN1KMT2AMAPT | |
| SCHEMBL877279 | 0.78 | KMT2A (0.73) | MEN1KMT2AMAPT | |
| SCHEMBL19020201 | 0.77 | MAPT (0.47) | CDC25AAPPMAPTSNCA | |
| Hydrochloric Acid SCHEMBL9878928 | 0.77 | KMT2A (0.71) | MEN1KMT2AMAPT | |
| SCHEMBL7680134 | 0.76 | MAPT (0.76) | APPMAPTSNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3394327-A1 | DNA-ENCODED CHEMICAL LIBRARY, USE THEREOF AND METHOD TO SYNTHESIZE THE LIBRARY | Technische Universität Dortmund (DE) | 2018-10-31 | — | — | EP | disclosed |
| WO-2017108741-A1 | DNA-ENCODED CHEMICAL LIBRARY, USE THEREOF AND METHOD TO SYNTHESIZE THE LIBRARY | TECHNISCHE UNIVERSITÄT DORTMUND (DE) | 2017-06-29 | — | — | WO | disclosed |
| EP-3184674-A1 | DNA-ENCODED CHEMICAL LIBRARY, USE THEREOF AND METHOD TO SYNTHESIZE THE LIBRARY | Technische Universität Dortmund (DE) | 2017-06-28 | — | — | EP | disclosed |