Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | APP | P05067 | 5/20 | 0.47 |
| ▸ | SNCA | P37840 | 5/20 | 0.47 |
| ▸ | CDC25A | P30304 | 9/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19020196 | 0.77 | CDC25A (0.54) | MAPTAPPSNCACDC25A | |
| SCHEMBL19030731 | 0.77 | CDC25A (0.54) | MAPTAPPSNCACDC25A | |
| SCHEMBL19020198 | 0.77 | CDC25A (0.54) | MAPTAPPSNCACDC25A | |
| SCHEMBL19020193 | 0.76 | CDC25A (0.49) | MAPTAPPSNCACDC25A | |
| SCHEMBL19020194 | 0.76 | CDC25A (0.49) | MAPTAPPSNCACDC25A | |
| SCHEMBL7680137 | 0.72 | MAPT (0.76) | MAPTAPPSNCAALDH1A1 | |
| SCHEMBL7680134 | 0.72 | MAPT (0.76) | MAPTAPPSNCAALDH1A1 | |
| SCHEMBL28706915 | 0.69 | ALDH1A1 (0.60) | MAPTAPPSNCAERBB2ALDH1A1 | |
| SCHEMBL28706911 | 0.69 | ALDH1A1 (0.60) | MAPTAPPSNCAERBB2ALDH1A1 | |
| SCHEMBL699152 | 0.68 | APP (0.57) | MAPTAPPSNCAERBB2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3394327-A1 | DNA-ENCODED CHEMICAL LIBRARY, USE THEREOF AND METHOD TO SYNTHESIZE THE LIBRARY | Technische Universität Dortmund (DE) | 2018-10-31 | — | — | EP | disclosed |
| WO-2017108741-A1 | DNA-ENCODED CHEMICAL LIBRARY, USE THEREOF AND METHOD TO SYNTHESIZE THE LIBRARY | TECHNISCHE UNIVERSITÄT DORTMUND (DE) | 2017-06-29 | — | — | WO | disclosed |
| EP-3184674-A1 | DNA-ENCODED CHEMICAL LIBRARY, USE THEREOF AND METHOD TO SYNTHESIZE THE LIBRARY | Technische Universität Dortmund (DE) | 2017-06-28 | — | — | EP | disclosed |