Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 7/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Acid SCHEMBL4338226 | 0.92 | ALDH1A1 (0.36) | KDM4EALDH1A1HPGDTSHRMEN1 | |
| Salicylic Acid SCHEMBL580943 | 0.87 | ALDH1A1 (0.45) | KDM4EALDH1A1HPGDGAASMN1; SMN2 | |
| SCHEMBL22091985 | 0.86 | MEN1 (0.34) | KDM4EALDH1A1HPGDGAASMN1; SMN2 | |
| Thiosalicylic Acid SCHEMBL28932205 | 0.85 | MAPT (0.36) | KDM4EALDH1A1HPGDMAPT | |
| Phthalic Acid SCHEMBL29142344 | 0.82 | ALDH1A1 (0.39) | ALDH1A1HTTCA1CA9LMNA | |
| Benzoic Acid SCHEMBL2523034 | 0.82 | CA2 (0.46) | ALDH1A1SMN1; SMN2MAPTTSHRLMNA | |
| Phthalic Acid SCHEMBL25403187 | 0.81 | ALDH1A1 (0.44) | ALDH1A1HTTLMNAKMT2AL3MBTL1 | |
| Phthalic Acid SCHEMBL25403191 | 0.81 | ALDH1A1 (0.44) | ALDH1A1HTTLMNAKMT2AL3MBTL1 | |
| Bicarbonate SCHEMBL2936301 | 0.79 | MEN1 (0.35) | SMN1; SMN2MEN1KMT2A | |
| Acetic Acid SCHEMBL302142 | 0.77 | MEN1 (0.37) | SMN1; SMN2CA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113260440-B | Process for the selective recovery of transition metals from organic residues | 艾尼股份公司 | 2023-07-14 | — | — | CN | disclosed |
| US-11286356-B2 | Method for fusing aramid/aramid fibres | PROIONIC GMBH (AT) | 2022-03-29 | — | — | US | disclosed |
| EP-3894037-A1 | PROCESS FOR THE SELECTIVE RECOVERY OF TRANSITION METALS FROM ORGANIC RESIDUES | ENI S.p.A. (IT) | 2021-10-20 | — | — | EP | disclosed |
| CN-113260440-A | Process for the selective recovery of transition metals from organic residues | 艾尼股份公司 | 2021-08-13 | — | — | CN | disclosed |
| US-20200270405-A1 | METHOD FOR FUSING ARAMID/ARAMID FIBRES | PROIONIC GMBH (AT) | 2020-08-27 | — | — | US | disclosed |
| US-10723849-B2 | Method for fusing aramid/aramid fibers | PROIONIC GMBH (AT) | 2020-07-28 | — | — | US | disclosed |
| WO-2020121220-A1 | PROCESS FOR THE SELECTIVE RECOVERY OF TRANSITION METALS FROM ORGANIC RESIDUES | ENI S.P.A. (IT) | 2020-06-18 | — | — | WO | disclosed |
| US-20170183460-A1 | METHOD FOR FUSING ARAMID/ARAMID FIBRES | PROIONIC GMBH (AT) | 2017-06-29 | — | — | US | disclosed |