Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL190257

CC(=O)OC[C@H]1O[C@H](O[C@]2(CO)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O.N

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 1/20 0.67
CCNB1 P14635 1/20 0.67
LDHA P00338 1/20 0.49
EPHX2 P34913 4/20 0.47
CA2 P00918 1/20 0.45
CA9 Q16790 1/20 0.45
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
PRKD3 O94806 1/20 0.37
PRKCG P05129 1/20 0.37
PRKCB P05771 1/20 0.37
PRKCA P17252 1/20 0.37
PRKCH P24723 1/20 0.37
PRKCI P41743 1/20 0.37
PRKCE Q02156 1/20 0.37
PRKCQ Q04759 1/20 0.37
PRKCZ Q05513 1/20 0.37
PRKCD Q05655 1/20 0.37
PRKD1 Q15139 1/20 0.37
ADORA1 P30542 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29279441 0.99 CDK1 (0.69) CDK1CCNB1LDHAEPHX2CA2
SCHEMBL891536 0.99 CDK1 (0.69) CDK1CCNB1LDHAEPHX2CA2
SCHEMBL28010776 0.98 CDK1 (0.67) CDK1CCNB1LDHAEPHX2CA2
Water SCHEMBL27148070 0.97 CDK1 (0.66) CDK1CCNB1LDHAEPHX2CA2
SCHEMBL27876247 0.90 CDK1 (0.66) CDK1CCNB1LDHAEPHX2CA2
SCHEMBL3134207 0.89 CDK1 (0.72) CDK1CCNB1LDHAEPHX2CA2
SCHEMBL9619718 0.89 CDK1 (0.72) CDK1CCNB1LDHAEPHX2CA2
SCHEMBL27473308 0.89 CDK1 (0.72) CDK1CCNB1LDHAEPHX2CA2
Benzoic Acid SCHEMBL28236823 0.89 CDK1 (0.57) CDK1CCNB1LDHAEPHX2CA2
SCHEMBL15756382 0.88 CDK1 (0.70) CDK1CCNB1LDHAEPHX2CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2401307-A1 METHODS OF PREPARING RENEWABLE BUTADIENE AND RENEWABLE ISOPRENE GEVO, Inc. (US) 2012-01-04 EP disclosed
WO-2010099201-A1 METHODS OF PREPARING RENEWABLE BUTADIENE AND RENEWABLE ISOPRENE GEVO, INC. (US) 2010-09-02 WO disclosed
US-20100216958-A1 Methods of Preparing Renewable Butadiene and Renewable Isoprene AGRI-ENERGY, LLC 2010-08-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100216958-A1 Methods of Preparing Renewable Butadiene and Renewable Isoprene ADH1A, ADH1C, FASN CDK1 2851/4885CCNB1 761/4885LDHA 1369/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.