SCHEMBL1903005

SCHEMBL1903005

[CH2]CC(C)CC1CCCCC1

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.34
CTSK P43235 7/20 0.34
CTSL P07711 4/20 0.33
CTSB P07858 4/20 0.33
CTSH P09668 3/20 0.32
LTA4H P09960 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11606375 0.87
SCHEMBL3155857 0.85 CYP1A2 (0.40) CYP1A2CTSKCTSLCTSBCTSH
SCHEMBL1899034 0.82 CTSK (0.33) CYP1A2CTSKCTSLCTSBCTSH
SCHEMBL7087843 0.80 CYP1A2 (0.37) CYP1A2CTSKCTSLCTSBCTSH
SCHEMBL2422889 0.78 SHBG (0.42) CYP1A2CTSKCTSLCTSB
SCHEMBL14261875 0.76 CTSK (0.39) CYP1A2CTSKCTSLCTSBCTSH
SCHEMBL12631778 0.76 CTSK (0.39) CYP1A2CTSKCTSLCTSBCTSH
SCHEMBL19003120 0.76 CYP1A2 (0.34) CYP1A2CTSKCTSLCTSBCTSH
SCHEMBL11746493 0.76 CYP1A2 (0.34) CYP1A2CTSKCTSLCTSBCTSH
SCHEMBL12632301 0.76 EPHX1 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019002788-A1 UREAS FOR SEPARATING URANIUM(VI) AND PLUTONIUM(IV) WITHOUT REDUCING THE PLUTONIUM(IV) COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2019-01-03 WO disclosed
WO-2014128206-A1 COMPOUNDS FOR USE IN INHIBITING HIV CAPSID ASSEMBLY Ruprecht-Karls-Universität Heidelberg (DE) 2014-08-28 WO disclosed
WO-2014128213-A1 COMPOUNDS FOR USE IN INHIBITING HIV CAPSID ASSEMBLY Ruprecht-Karls-Universität Heidelberg (DE) 2014-08-28 WO disclosed
EP-2319509-A1 Method of Inhibiting remnant lipoprotein production Japan Tobacco, Inc. (JP) 2011-05-11 EP disclosed
EP-1670446-A2 METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION JAPAN TOBACCO INC. (JP) 2006-06-21 EP disclosed
EP-1603553-A2 PHARMACEUTICAL COMPOSITIONS OF CETP INHIBITORS JAPAN TOBACCO INC. (JP) 2005-12-14 EP disclosed
WO-2005030185-A2 METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION JAPAN TOBACCO INC. (JP) 2005-04-07 WO disclosed
WO-2004082593-A2 PHARMACEUTICAL COMPOSITIONS OF CETP INHIBITORS JAPAN TOBACCO INC. (JP) 2004-09-30 WO disclosed
EP-0555331-A1 N-SUBSTITUTED IMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS. SEARLE & CO (US) 1993-08-18 EP disclosed