Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA7 | P43166 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28553416 | 0.82 | GAA (0.41) | GAAMAOACHRM2CHRM3HTR2C | |
| SCHEMBL7148262 | 0.80 | ALDH1A1 (0.49) | GAAADRB3ALDH1A1CYP3A4LMNA | |
| SCHEMBL16973272 | 0.77 | ALDH1A1 (0.36) | GAAALDH1A1CA2CYP3A4LMNA | |
| SCHEMBL29082623 | 0.74 | PBRM1 (0.45) | GAAALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL5571825 | 0.73 | LMNA (0.58) | GAAMAOACHRM2HTR3AKCNH2 | |
| SCHEMBL1513963 | 0.71 | TSHR (0.53) | ALDH1A1CA2CYP3A4LMNAKDM4E | |
| SCHEMBL30120579 | 0.71 | PDE2A (0.39) | GAAALDH1A1CYP3A4LMNAMAPT | |
| SCHEMBL11402718 | 0.71 | PDE2A (0.39) | GAAALDH1A1CYP3A4LMNAMAPT | |
| SCHEMBL3110030 | 0.71 | ALDH1A1 (0.60) | GAAALDH1A1CYP3A4MAPTKDM4E | |
| SCHEMBL2128862 | 0.71 | ALDH1A1 (0.49) | GAAALDH1A1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493702-B1 | SECURITY DOCUMENT | BANK OF ENGLAND (GB) | 2014-12-31 | — | — | EP | disclosed |
| EP-2493702-A1 | SECURITY DOCUMENT | THE GOVERNOR AND COMPANY OF THE BANK OF ENGLAND (GB) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011051712-A1 | SECURITY DOCUMENT | THE GOVERNOR & COMPANY OF THE BANK OF ENGLAND (GB) | 2011-05-05 | — | — | WO | disclosed |