Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 9/20 | 0.50 |
| ▸ | DRD5 | P21918 | 9/20 | 0.50 |
| ▸ | DRD2 | P14416 | 8/20 | 0.50 |
| ▸ | DRD3 | P35462 | 7/20 | 0.50 |
| ▸ | DRD4 | P21917 | 5/20 | 0.49 |
| ▸ | MAOA | P21397 | 4/20 | 0.48 |
| ▸ | MAOB | P27338 | 4/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12363785 | 0.94 | MAOA (0.59) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL2625799 | 0.92 | MAOA (0.55) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL8342556 | 0.81 | — | — | |
| SCHEMBL6952918 | 0.77 | NOTUM (0.59) | NOTUMALDH1A1 | |
| Ethane SCHEMBL28782548 | 0.77 | NPC1 (0.49) | NOTUMALDH1A1 | |
| SCHEMBL5245075 | 0.77 | NPC1 (0.47) | ALDH1A1 | |
| SCHEMBL31593929 | 0.77 | NPC1 (0.52) | ALDH1A1 | |
| SCHEMBL30634164 | 0.77 | NPC1 (0.47) | ALDH1A1 | |
| SCHEMBL798296 | 0.77 | NPC1 (0.52) | ALDH1A1 | |
| SCHEMBL5741261 | 0.76 | ALDH1A1 (0.49) | DRD1DRD5DRD2DRD3NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2322162-A1 | 5HT2C receptor modulator compositions and methods of use | Arena Pharmaceuticals, Inc. (US) | 2011-05-18 | — | — | EP | disclosed |