Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6574037 | 0.89 | CA1 (0.37) | CA14CA1CA12CA9EPHX1 | |
| SCHEMBL16371366 | 0.77 | CA1 (0.33) | CA1CA12CA9CA2 | |
| SCHEMBL1905087 | 0.74 | CA14 (0.35) | CA14CA1CA12CA9CA2 | |
| SCHEMBL805360 | 0.73 | ACACB (0.37) | CA1ACACBCA2 | |
| SCHEMBL16388800 | 0.72 | ALDH1A1 (0.39) | CA1CA12CA9ACACBCA2 | |
| SCHEMBL5048218 | 0.72 | CA14 (0.43) | CA14CA1CA12CA9CA2 | |
| SCHEMBL4799446 | 0.72 | CA14 (0.43) | CA14CA1CA12CA9CA2 | |
| SCHEMBL6464487 | 0.72 | CA14 (0.43) | CA14CA1CA12CA9CA2 | |
| SCHEMBL5122365 | 0.71 | ITGB3 (0.40) | — | |
| SCHEMBL5131032 | 0.71 | ITGB3 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051671-A1 | AMINOPYRIDINE DERIVATIVES AS KALLIKREIN INHIBITORS | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | disclosed |