Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | DNM2 | P50570 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2638660 | 0.85 | NAAA (0.59) | HTTTSHRHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL771801 | 0.84 | KDM4E (0.57) | HTTHPGDALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL19033250 | 0.82 | HTT (0.48) | HTTTSHRALOX5DNM2HPGD | |
| SCHEMBL24844329 | 0.81 | MAPK1 (0.42) | HTTTSHRHPGDNPC1ALDH1A1 | |
| SCHEMBL26787499 | 0.81 | NAAA (0.55) | HTTTSHRHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL24843418 | 0.80 | MAPK1 (0.41) | HTTTSHRHPGDALDH1A1HSD17B10 | |
| SCHEMBL24844315 | 0.80 | MAPK1 (0.41) | HTTTSHRHPGDALDH1A1HSD17B10 | |
| SCHEMBL24106106 | 0.79 | LCK (0.41) | HTTTSHRNPC1MAPTNPSR1 | |
| SCHEMBL17911678 | 0.79 | MAPK1 (0.40) | HTTTSHRALOX5MAPTMAPK1 | |
| SCHEMBL772102 | 0.79 | HTT (0.58) | HTTHPGDALDH1A1HSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9688881-B1 | Low-melt polyamic acid based powder coatings | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 2017-06-27 | — | — | US | disclosed |
| US-9688881-B1 | Low-melt polyamic acid based powder coatings | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 2017-06-27 | — | — | US | disclosed |