Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 9/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.57 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | LGALS1 | P09382 | 3/20 | 0.43 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19042820 | 0.89 | FTO (0.62) | FTOHPGDMAPTMEN1CYP2C19 | |
| SCHEMBL16982918 | 0.87 | FTO (0.60) | FTOHPGDMAPTMEN1CYP2C19 | |
| SCHEMBL3499473 | 0.87 | ALB (0.56) | FTOHPGDMAPTMEN1CYP2C19 | |
| SCHEMBL17956704 | 0.86 | FTO (0.60) | FTOHPGDMAPTMEN1CYP2C19 | |
| SCHEMBL30520076 | 0.84 | FTO (0.58) | FTOHPGDMAPTMEN1CYP2C19 | |
| SCHEMBL15326935 | 0.84 | FTO (0.58) | FTOHPGDMAPTMEN1CYP2C19 | |
| SCHEMBL30595817 | 0.84 | FTO (0.58) | FTOHPGDMAPTMEN1CYP2C19 | |
| SCHEMBL15059064 | 0.84 | FTO (0.70) | FTOHPGDMAPTMEN1CYP2C19 | |
| SCHEMBL29995323 | 0.84 | FTO (0.70) | FTOHPGDMAPTMEN1CYP2C19 | |
| SCHEMBL24723090 | 0.84 | FTO (0.51) | FTOHPGDMAPTMEN1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170182176-A1 | POLYMERS HAVING THERAPEUTICALLY ACTIVE AGENTS CONJUGATED THERETO, PROCESSES OF PREPARING SAME AND USES THEREOF | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2017-06-29 | — | — | US | disclosed |
| US-9687562-B2 | Polymers having therapeutically active agents conjugated thereto, processes of preparing same and uses thereof | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2017-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170182176-A1 | POLYMERS HAVING THERAPEUTICALLY ACTIVE AGENTS CONJUGATED THERETO, PROCESSES OF PREPARING SAME AND USES THEREOF | CD47, VCAM1, CD44 | FTO 3855/4885HPGD 1223/4885MAPT 1769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.