Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.86 |
| ▸ | ESR1 | P03372 | 4/20 | 0.86 |
| ▸ | TSHR | P16473 | 2/20 | 0.86 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.86 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.86 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.86 |
| ▸ | KDR | P35968 | 1/20 | 0.86 |
| ▸ | LMNA | P02545 | 3/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.70 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.70 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.66 |
| ▸ | CA12 | O43570 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | CA7 | P43166 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL28097309 | 0.95 | LMNA (0.86) | ALDH1A1ESR1TSHRTDP1CHRM1 | |
| Propylparaben SCHEMBL429594 | 0.93 | ESR1 (1.00) | ALDH1A1ESR1TSHRTDP1CHRM1 | |
| Propylparaben SCHEMBL977 | 0.93 | ESR1 (1.00) | ALDH1A1ESR1TSHRTDP1CHRM1 | |
| Propylparaben SCHEMBL11484158 | 0.92 | ALDH1A1 (0.78) | ALDH1A1ESR1TSHRTDP1CHRM1 | |
| Propylparaben SCHEMBL8427362 | 0.92 | ALDH1A1 (0.78) | ALDH1A1ESR1TSHRTDP1CHRM1 | |
| Propylparaben SCHEMBL28219717 | 0.92 | ESR1 (0.78) | ALDH1A1ESR1TSHRTDP1CHRM1 | |
| Propylparaben SCHEMBL7668086 | 0.92 | ALDH1A1 (0.83) | ALDH1A1ESR1TSHRTDP1CHRM1 | |
| Propylparaben SCHEMBL6129826 | 0.91 | ALDH1A1 (0.89) | ALDH1A1ESR1TSHRTDP1CHRM1 | |
| Propylparaben SCHEMBL6315856 | 0.91 | ESR1 (0.96) | ALDH1A1ESR1TSHRTDP1CHRM1 | |
| Propylparaben SCHEMBL1135822 | 0.91 | ESR1 (0.96) | ALDH1A1ESR1TSHRTDP1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178489-B2 | Liquid, in a buffer which has a pH of 4.8 to 6.7; Aviptadil (VIP, vasoactive intestinal peptide); storage stability; use treating hypertension, cancer, respiratory system disorders, genetic disorders, neurodegenerative diseases | MONDOBIOTECH AG (CH) | 2012-05-15 | — | — | US | claimed |
| EP-1855661-B1 | FORMULATION FOR AVIPTADIL | MONDOBIOTECH AG (CH) | 2011-05-04 | — | — | EP | claimed |
| US-20080161237-A1 | Formulation For a Viptadil | RELIEF THERAPEUTICS INTERNATIONAL SA (CH) | 2008-07-03 | — | — | US | claimed |
| EP-1855661-A1 | FORMULATION FOR AVIPTADIL | MondoBIOTECH Licensing Out AG (CH) | 2007-11-21 | — | — | EP | claimed |
| WO-2006094764-A1 | FORMULATION FOR AVIPTADIL | MONDOBIOTECH LICENSING OUT AG (CH) | 2006-09-14 | — | — | WO | claimed |
| CN-103517909-A | Novel anti-platelet compound addition salt | GUANGZHOU HEERSHI PHARMA DEV CO LTD | 2014-01-15 | — | — | CN | disclosed |