Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 5/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 5/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6947872 | 0.73 | QDPR (0.36) | CARM1PRMT6 | |
| SCHEMBL9644027 | 0.70 | QDPR (0.39) | SIGMAR1 | |
| SCHEMBL14389062 | 0.69 | ACHE (0.68) | CARM1PRMT6SIGMAR1ACHEALDH1A1 | |
| SCHEMBL10934333 | 0.69 | HRH3 (0.44) | CARM1PRMT6HRH3ACHE | |
| SCHEMBL13783321 | 0.69 | QDPR (0.42) | — | |
| SCHEMBL20459540 | 0.68 | HRH3 (0.53) | L3MBTL1HRH3SIGMAR1ACHE | |
| SCHEMBL13599361 | 0.67 | QDPR (0.37) | SIGMAR1 | |
| SCHEMBL785856 | 0.67 | HRH3 (0.60) | L3MBTL1HRH3SIGMAR1ACHE | |
| SCHEMBL27763800 | 0.67 | HTR2A (0.56) | CARM1PRMT6L3MBTL1HRH3 | |
| SCHEMBL3424079 | 0.66 | QDPR (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9688633-B2 | Substituted piperidines with antiparasitic activity | INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT (FR) | 2017-06-27 | — | — | US | disclosed |