Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | DGKA | P23743 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | HRH2 | P25021 | 2/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19034571 | 0.92 | DGKA (0.50) | ALDH1A1L3MBTL1DGKAMAPTMAPK1 | |
| SCHEMBL12879889 | 0.88 | PAOX (0.49) | ALDH1A1L3MBTL1DGKAMAPTMAPK1 | |
| SCHEMBL31661129 | 0.87 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1DGKAMAPTMAPK1 | |
| SCHEMBL10084759 | 0.86 | CYP1A2 (0.50) | ALDH1A1L3MBTL1MAPK1SMN1; SMN2CYP1A2 | |
| SCHEMBL31661139 | 0.85 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1DGKAMAPTMAPK1 | |
| SCHEMBL7509641 | 0.85 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1DGKAMAPTMAPK1 | |
| SCHEMBL31661130 | 0.83 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1DGKAMAPTMAPK1 | |
| SCHEMBL1855324 | 0.82 | CYP1A2 (0.53) | ALDH1A1L3MBTL1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL674334 | 0.82 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1DGKAMAPTMAPK1 | |
| SCHEMBL419258 | 0.82 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1DGKAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9687448-B2 | Nucleic acid lipid particle formulations | ALNYLAM PHARMACEUTICALS, INC. (US) | 2017-06-27 | — | — | US | disclosed |