Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | MASP2 | O00187 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | CPB1 | P15086 | 1/20 | 0.42 |
| ▸ | FPR1 | P21462 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1903456 | 1.00 | NAMPT (0.50) | NAMPTMEN1KMT2AMAPTJAK2 | |
| SCHEMBL1906790 | 0.90 | KLKB1 (0.49) | NAMPTMEN1KMT2AHDAC1CTSS | |
| SCHEMBL1906788 | 0.90 | KLKB1 (0.49) | NAMPTMEN1KMT2AHDAC1CTSS | |
| SCHEMBL1906792 | 0.85 | OPRD1 (0.47) | CTSSCTSKMASP2HRH4LCK | |
| SCHEMBL1906797 | 0.85 | OPRD1 (0.47) | CTSSCTSKMASP2HRH4LCK | |
| SCHEMBL1905135 | 0.84 | PSMB8 (0.53) | CTSSCTSKMASP2HRH4LCK | |
| SCHEMBL1905132 | 0.84 | PSMB8 (0.53) | CTSSCTSKMASP2HRH4LCK | |
| SCHEMBL1904790 | 0.83 | OPRD1 (0.48) | HDAC1CTSSCTSKMASP2LCK | |
| SCHEMBL1902805 | 0.83 | OPRD1 (0.46) | CTSSCTSKMASP2HRH4LCK | |
| SCHEMBL1902802 | 0.83 | OPRD1 (0.46) | CTSSCTSKMASP2HRH4LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051671-A1 | AMINOPYRIDINE DERIVATIVES AS KALLIKREIN INHIBITORS | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | disclosed |