Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 10/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | DGKA | P23743 | 1/20 | 0.36 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10081247 | 0.89 | ALDH1A1 (0.48) | ALDH1A1ALOX15TDP1USP2ALOX5 | |
| SCHEMBL19861337 | 0.87 | CYP1A2 (0.50) | ALDH1A1ALOX15TDP1USP2CYP1A2 | |
| SCHEMBL10084982 | 0.82 | ALOX5 (0.60) | ALDH1A1ALOX15TDP1USP2ALOX5 | |
| SCHEMBL11045153 | 0.82 | ALOX5 (0.60) | ALDH1A1ALOX15TDP1USP2ALOX5 | |
| SCHEMBL11045151 | 0.82 | ALOX5 (0.60) | ALDH1A1ALOX15TDP1USP2ALOX5 | |
| SCHEMBL11045194 | 0.82 | ALOX5 (0.60) | ALDH1A1ALOX15TDP1USP2ALOX5 | |
| SCHEMBL16174245 | 0.82 | ALOX5 (0.60) | ALDH1A1ALOX15TDP1USP2ALOX5 | |
| SCHEMBL16358138 | 0.80 | CYP1A2 (0.53) | ALDH1A1ALOX15TDP1USP2CYP1A2 | |
| SCHEMBL18746504 | 0.80 | CYP1A2 (0.61) | ALDH1A1ALOX15TDP1USP2ALOX5 | |
| SCHEMBL4803790 | 0.78 | ALDH1A1 (0.49) | ALDH1A1ALOX15TDP1USP2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9687448-B2 | Nucleic acid lipid particle formulations | ALNYLAM PHARMACEUTICALS, INC. (US) | 2017-06-27 | — | — | US | disclosed |