Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ADH1B | P00325 | 1/20 | 0.31 |
| ▸ | ADH1C | P00326 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
| ▸ | ADH4 | P08319 | 1/20 | 0.31 |
| ▸ | ADH7 | P40394 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21514093 | 0.83 | PRSS1 (0.37) | ADAKDRMEN1KMT2ANPSR1 | |
| SCHEMBL17943853 | 0.76 | NPC1 (0.42) | KDRNPSR1 | |
| SCHEMBL22255172 | 0.72 | LMNA (0.34) | MEN1KMT2ANPSR1 | |
| SCHEMBL19504430 | 0.69 | GAA (0.41) | GAA | |
| SCHEMBL293669 | 0.68 | — | — | |
| SCHEMBL255119 | 0.67 | — | — | |
| SCHEMBL24884612 | 0.66 | THRB (0.39) | GAA | |
| SCHEMBL22129693 | 0.64 | ACE2 (0.62) | ACE2ADH1BADH1CADH1AADH4 | |
| SCHEMBL20835139 | 0.64 | ACE2 (0.62) | ACE2ADH1BADH1CADH1AADH4 | |
| SCHEMBL20506756 | 0.64 | ACE2 (0.62) | ACE2ADH1BADH1CADH1AADH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9688669-B2 | Oxazolidinones as modulators of mGluR5 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-06-27 | — | — | US | disclosed |