SCHEMBL19037149

SCHEMBL19037149

c1ccc(-n2c3cc4ccccc4cc3c3ccc4c5ccccc5n(-c5nc(-c6ccc7ccccc7c6)c6ccccc6n5)c4c32)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
KDM4E B2RXH2 3/20 0.36
HPGD P15428 3/20 0.36
MAPT P10636 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
L3MBTL1 Q9Y468 4/20 0.35
ATM Q13315 2/20 0.35
LMNA P02545 2/20 0.34
MAPK1 P28482 2/20 0.34
POLB P06746 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
PIK3CD O00329 1/20 0.33
PIK3CA P42336 1/20 0.33
MTOR P42345 1/20 0.33
TUBB4A P04350 1/20 0.33
TUBB P07437 1/20 0.33
TUBA3C P0DPH7 1/20 0.33
TUBA1B P68363 1/20 0.33
TUBA4A P68366 1/20 0.33
TUBB4B P68371 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19359931 0.96 KDM4E (0.39) ALDH1A1KDM4EHPGDMAPTNPSR1
SCHEMBL17990581 0.92 ALDH1A1 (0.44) ALDH1A1KDM4EHPGDMAPTNPSR1
SCHEMBL21212935 0.92 L3MBTL1 (0.37) ALDH1A1KDM4EHPGDMAPTNPSR1
SCHEMBL21168823 0.90 KDM4E (0.35) ALDH1A1KDM4EHPGDMAPTNPSR1
SCHEMBL21168829 0.90 L3MBTL1 (0.37) ALDH1A1KDM4EHPGDMAPTNPSR1
SCHEMBL21168807 0.89 L3MBTL1 (0.40) ALDH1A1KDM4EHPGDMAPTNPSR1
SCHEMBL21168815 0.89 L3MBTL1 (0.40) ALDH1A1KDM4EHPGDMAPTNPSR1
SCHEMBL21213313 0.89 L3MBTL1 (0.42) ALDH1A1KDM4EHPGDMAPTNPSR1
SCHEMBL21213425 0.89 L3MBTL1 (0.42) ALDH1A1KDM4EHPGDMAPTNPSR1
SCHEMBL21213716 0.89 ALDH1A1 (0.43) ALDH1A1KDM4EHPGDMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170186975-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-29 US disclosed
US-20170186975-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-29 US disclosed