Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 6/20 | 0.38 |
| ▸ | SLC8A1 | P32418 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 3/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | CTSC | P53634 | 4/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | MC3R | P41968 | 1/20 | 0.36 |
| ▸ | MC1R | Q01726 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1431919 | 0.86 | MASP2 (0.45) | MMEGID4HTR2CHTR2BHTR2A | |
| SCHEMBL1432761 | 0.84 | MASP2 (0.44) | MMEGID4HTR2CHTR2BHTR2A | |
| SCHEMBL1905042 | 0.83 | MEN1 (0.39) | — | |
| SCHEMBL1902249 | 0.83 | MEN1 (0.39) | — | |
| SCHEMBL1904624 | 0.83 | MEN1 (0.39) | — | |
| SCHEMBL1902540 | 0.82 | MEN1 (0.38) | HDAC1MC4RMC3R | |
| SCHEMBL1907208 | 0.82 | MEN1 (0.38) | HDAC1MC4RMC3R | |
| SCHEMBL1905007 | 0.81 | MEN1 (0.40) | — | |
| SCHEMBL1905882 | 0.81 | MEN1 (0.38) | — | |
| SCHEMBL1905746 | 0.81 | MEN1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051673-A1 | AMINOTHIAZOLE DERIVATIVES USEFUL AS KLK1 INHIBITORS | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | claimed |
| WO-2011051673-A1 | AMINOTHIAZOLE DERIVATIVES USEFUL AS KLK1 INHIBITORS | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | disclosed |