Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 8/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1904003 | 1.00 | MTNR1A (0.53) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL1904539 | 0.90 | PTGDR2 (0.49) | MTNR1AMTNR1BCYP2C9PTGDR2 | |
| SCHEMBL1904540 | 0.90 | PTGDR2 (0.49) | MTNR1AMTNR1BCYP2C9PTGDR2 | |
| SCHEMBL833776 | 0.85 | PTGDR2 (0.59) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL833777 | 0.85 | PTGDR2 (0.59) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL1902517 | 0.84 | PTGDR2 (0.51) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL1902518 | 0.84 | PTGDR2 (0.51) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL2493727 | 0.82 | PTGDR2 (0.46) | PTGDR2 | |
| SCHEMBL2493728 | 0.82 | PTGDR2 (0.46) | PTGDR2 | |
| SCHEMBL1903734 | 0.81 | PTGDR2 (0.50) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2051962-B1 | (3-AMINO-1,2,3,4-TETRAHYDRO-9H-CARBAZOL-9-YL)-ACETIC ACID DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2011-10-26 | — | — | EP | disclosed |
| EP-2316824-A1 | (3-Amino-1,2,3,4-tetrahydro-9H-carbazoI-9-yl)-acetic acid derivates | Actelion Pharmaceuticals Ltd. (CH) | 2011-05-04 | — | — | EP | disclosed |